Cutaneous reactions due to antihypertensive drugs
Out of a total of 1147 patients on antihypertensive drugs, 23 (2.04%) developed adverse cutaneous drug reactions (ACDR). The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit. The second most common group was calcium channel b...
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2006-01-01
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doaj-2bfeb0eaf0384f22b54214dbcde17ce32020-11-24T23:46:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51542006-01-01513189191Cutaneous reactions due to antihypertensive drugsUpadhayai JNangia AnupMukhija RMisra MukumMohan LalitSingh KOut of a total of 1147 patients on antihypertensive drugs, 23 (2.04%) developed adverse cutaneous drug reactions (ACDR). The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit. The second most common group was calcium channel blockers with amlodipine as the commonest offender. The most common patterns of ACDR observed included urticaria followed by lichenoid drug eruption (LDE). We noted 2 new patterns of reactions; (i) one patient developed brownish blue pigmentation of nails while on atenolol for 3 years, which resolved in 4 months after withdrawal and (ii) another patient on amlodipine for 8 years developed Schamberg′s like purpuric pigmentation, which resolved on withdrawal of drug within 3 months. These findings have not been reported in the literature earlier. This study is presented for paucity of Indian data on ACDR due to antihypertensive drugs, and remarkable advancement in area of cardiovascular and antihypertensive pharmacology and a large number of population taking antihypertensive drugs.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2006;volume=51;issue=3;spage=189;epage=191;aulast=UpadhayaiAdverse cutaneous drug reactionlichenoid drug eruptionantihypertensive drugs |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Upadhayai J Nangia Anup Mukhija R Misra Mukum Mohan Lalit Singh K |
spellingShingle |
Upadhayai J Nangia Anup Mukhija R Misra Mukum Mohan Lalit Singh K Cutaneous reactions due to antihypertensive drugs Indian Journal of Dermatology Adverse cutaneous drug reaction lichenoid drug eruption antihypertensive drugs |
author_facet |
Upadhayai J Nangia Anup Mukhija R Misra Mukum Mohan Lalit Singh K |
author_sort |
Upadhayai J |
title |
Cutaneous reactions due to antihypertensive drugs |
title_short |
Cutaneous reactions due to antihypertensive drugs |
title_full |
Cutaneous reactions due to antihypertensive drugs |
title_fullStr |
Cutaneous reactions due to antihypertensive drugs |
title_full_unstemmed |
Cutaneous reactions due to antihypertensive drugs |
title_sort |
cutaneous reactions due to antihypertensive drugs |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Dermatology |
issn |
0019-5154 |
publishDate |
2006-01-01 |
description |
Out of a total of 1147 patients on antihypertensive drugs, 23 (2.04%) developed adverse cutaneous drug reactions (ACDR). The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit. The second most common group was calcium channel blockers with amlodipine as the commonest offender. The most common patterns of ACDR observed included urticaria followed by lichenoid drug eruption (LDE). We noted 2 new patterns of reactions; (i) one patient developed brownish blue pigmentation of nails while on atenolol for 3 years, which resolved in 4 months after withdrawal and (ii) another patient on amlodipine for 8 years developed Schamberg′s like purpuric pigmentation, which resolved on withdrawal of drug within 3 months. These findings have not been reported in the literature earlier. This study is presented for paucity of Indian data on ACDR due to antihypertensive drugs, and remarkable advancement in area of cardiovascular and antihypertensive pharmacology and a large number of population taking antihypertensive drugs. |
topic |
Adverse cutaneous drug reaction lichenoid drug eruption antihypertensive drugs |
url |
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2006;volume=51;issue=3;spage=189;epage=191;aulast=Upadhayai |
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