Induction of resident memory T cells enhances the efficacy of cancer vaccine
Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better surv...
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Nature Publishing Group
2017-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15221 |
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doaj-2c09610a4b334c25a37a0973fab8481f2021-05-11T07:12:02ZengNature Publishing GroupNature Communications2041-17232017-05-018111110.1038/ncomms15221Induction of resident memory T cells enhances the efficacy of cancer vaccineMevyn Nizard0Hélène Roussel1Mariana O. Diniz2Soumaya Karaki3Thi Tran4Thibault Voron5Estelle Dransart6Federico Sandoval7Marc Riquet8Bastien Rance9Elie Marcheteau10Elizabeth Fabre11Marion Mandavit12Magali Terme13Charlotte Blanc14Jean-Baptiste Escudie15Laure Gibault16Françoise Le Pimpec Barthes17Clemence Granier18Luis C. S. Ferreira19Cecile Badoual20Ludger Johannes21Eric Tartour22INSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéInstitut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery UnitINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéHopital Europeen Georges Pompidou, Chrirurgie Thoracique Générale, Oncologique et TransplantationDepartment of Medical Bioinformatics, Hopital Européen Georges PompidouINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéDepartement of Medical Oncology, Hopital Européen Georges PompidouINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéDepartment of Medical Bioinformatics, Hopital Européen Georges PompidouDepartment of Pathology, Hopital Européen Georges PompidouHopital Europeen Georges Pompidou, Chrirurgie Thoracique Générale, Oncologique et TransplantationINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéInstitute of Biomedical Sciences, University of Sao Paulo, Av Prof Lineu PrestesINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéInstitut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery UnitINSERM U970, Université Paris Descartes, Sorbonne Paris-CitéResident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better survival.https://doi.org/10.1038/ncomms15221 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour |
| spellingShingle |
Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour Induction of resident memory T cells enhances the efficacy of cancer vaccine Nature Communications |
| author_facet |
Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour |
| author_sort |
Mevyn Nizard |
| title |
Induction of resident memory T cells enhances the efficacy of cancer vaccine |
| title_short |
Induction of resident memory T cells enhances the efficacy of cancer vaccine |
| title_full |
Induction of resident memory T cells enhances the efficacy of cancer vaccine |
| title_fullStr |
Induction of resident memory T cells enhances the efficacy of cancer vaccine |
| title_full_unstemmed |
Induction of resident memory T cells enhances the efficacy of cancer vaccine |
| title_sort |
induction of resident memory t cells enhances the efficacy of cancer vaccine |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-05-01 |
| description |
Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better survival. |
| url |
https://doi.org/10.1038/ncomms15221 |
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