Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves

Apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanol extract of Macaranga gigantifolia leaves. Isolation and purification of apigenin conducted using column and centrifugal chromatography and chemical structure characterized based on spectroscopic data. In vit...

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Bibliographic Details
Main Authors:	Sofa Fajriah, Megawati, Akhmad Darmawan
Format:	Article
Language:	English
Published:	University of Brawijaya 2016-04-01
Series:	Journal of Tropical Life Science
Subjects:	anticancer apigenin flavones Macaranga gigantifolia murine leukemia P-388 cell line
Online Access:	http://jtrolis.ub.ac.id/index.php/jtrolis/article/view/300/pdf

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spelling	doaj-2c1cb3c263144431957cd54554b8d8002020-11-24T22:30:01ZengUniversity of BrawijayaJournal of Tropical Life Science2087-55172087-55172016-04-016179Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves Sofa Fajriah0Megawati1Akhmad Darmawan2Indonesian Institute of Sciences (LIPI)Indonesian Institute of Sciences (LIPI)Indonesian Institute of Sciences (LIPI)Apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanol extract of Macaranga gigantifolia leaves. Isolation and purification of apigenin conducted using column and centrifugal chromatography and chemical structure characterized based on spectroscopic data. In vitro anticancer activity test against murine leukimia P-388 cell line showed potential activity as anticancer with IC50 14.13 µg/mL. http://jtrolis.ub.ac.id/index.php/jtrolis/article/view/300/pdfanticancerapigeninflavonesMacaranga gigantifoliamurine leukemia P-388 cell line
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sofa Fajriah Megawati Akhmad Darmawan
spellingShingle	Sofa Fajriah Megawati Akhmad Darmawan Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves Journal of Tropical Life Science anticancer apigenin flavones Macaranga gigantifolia murine leukemia P-388 cell line
author_facet	Sofa Fajriah Megawati Akhmad Darmawan
author_sort	Sofa Fajriah
title	Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves
title_short	Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves
title_full	Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves
title_fullStr	Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves
title_full_unstemmed	Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves
title_sort	apigenin, an anticancer isolated from macaranga gigantifolia leaves
publisher	University of Brawijaya
series	Journal of Tropical Life Science
issn	2087-5517 2087-5517
publishDate	2016-04-01
description	Apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanol extract of Macaranga gigantifolia leaves. Isolation and purification of apigenin conducted using column and centrifugal chromatography and chemical structure characterized based on spectroscopic data. In vitro anticancer activity test against murine leukimia P-388 cell line showed potential activity as anticancer with IC50 14.13 µg/mL.
topic	anticancer apigenin flavones Macaranga gigantifolia murine leukemia P-388 cell line
url	http://jtrolis.ub.ac.id/index.php/jtrolis/article/view/300/pdf
work_keys_str_mv	AT sofafajriah apigeninananticancerisolatedfrommacarangagigantifolialeaves AT megawati apigeninananticancerisolatedfrommacarangagigantifolialeaves AT akhmaddarmawan apigeninananticancerisolatedfrommacarangagigantifolialeaves
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Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves

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