Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material

Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material

The extent of epithelial cellular material (ECM) occurring in venous blood samples after diagnostic core needle biopsy (CNB) was studied in 23 patients with CNB diagnosed prostate cancer without provable metastases and 15 patients without cancer. The data show a significant increase of ECM in the pe...

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Main Authors: Sam Ladjevardi, Gert Auer, Juan Castro, Christer Ericsson, Anders Zetterberg, Michael Häggman, Hans Wiksell, Håkan Jorulf
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2014/707529
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spelling doaj-2c1ded2190d74d01b48cebff8c54d5ab2020-11-24T22:00:37ZengHindawi LimitedDisease Markers0278-02401875-86302014-01-01201410.1155/2014/707529707529Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular MaterialSam Ladjevardi0Gert Auer1Juan Castro2Christer Ericsson3Anders Zetterberg4Michael Häggman5Hans Wiksell6Håkan Jorulf7Surgical Science, Uppsala University, 751 85 Uppsala, SwedenKarolinska Biomic Center, Karolinska Institutet, 171 76 Stockholm, SwedenDepartment of Oncology-Pathology, CCK R8:04, Karolinska Institutet, 171 76 Stockholm, SwedenDepartment of Oncology-Pathology, CCK R8:04, Karolinska Institutet, 171 76 Stockholm, SwedenDepartment of Oncology-Pathology, CCK R8:04, Karolinska Institutet, 171 76 Stockholm, SwedenSurgical Science, Uppsala University, 751 85 Uppsala, SwedenDepartment of Molecular Medicine and Surgery, Karolinska Institutet, c/o Hans Wiksell, Comair AB, P.O. Box 39011, 100 54 Stockholm, SwedenRadiology, Oncology and Radiation Science, Section of Radiology, Uppsala University, 751 85 Uppsala, SwedenThe extent of epithelial cellular material (ECM) occurring in venous blood samples after diagnostic core needle biopsy (CNB) was studied in 23 patients with CNB diagnosed prostate cancer without provable metastases and 15 patients without cancer. The data show a significant increase of ECM in the peripheral blood sampled 20 seconds or 30 minutes after the last of 10 CNB procedures compared to the number of ECM detectable in the blood samples taken before the performance of CNB. The data indicate that diagnostic CNB of prostate cancer causes an extensive tissue trauma with a potential risk of cancer cell dissemination.http://dx.doi.org/10.1155/2014/707529
collection DOAJ
language English
format Article
sources DOAJ
author Sam Ladjevardi
Gert Auer
Juan Castro
Christer Ericsson
Anders Zetterberg
Michael Häggman
Hans Wiksell
Håkan Jorulf
spellingShingle Sam Ladjevardi
Gert Auer
Juan Castro
Christer Ericsson
Anders Zetterberg
Michael Häggman
Hans Wiksell
Håkan Jorulf
Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
Disease Markers
author_facet Sam Ladjevardi
Gert Auer
Juan Castro
Christer Ericsson
Anders Zetterberg
Michael Häggman
Hans Wiksell
Håkan Jorulf
author_sort Sam Ladjevardi
title Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
title_short Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
title_full Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
title_fullStr Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
title_full_unstemmed Prostate Biopsy Sampling Causes Hematogenous Dissemination of Epithelial Cellular Material
title_sort prostate biopsy sampling causes hematogenous dissemination of epithelial cellular material
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2014-01-01
description The extent of epithelial cellular material (ECM) occurring in venous blood samples after diagnostic core needle biopsy (CNB) was studied in 23 patients with CNB diagnosed prostate cancer without provable metastases and 15 patients without cancer. The data show a significant increase of ECM in the peripheral blood sampled 20 seconds or 30 minutes after the last of 10 CNB procedures compared to the number of ECM detectable in the blood samples taken before the performance of CNB. The data indicate that diagnostic CNB of prostate cancer causes an extensive tissue trauma with a potential risk of cancer cell dissemination.
url http://dx.doi.org/10.1155/2014/707529
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AT juancastro prostatebiopsysamplingcauseshematogenousdisseminationofepithelialcellularmaterial
AT christerericsson prostatebiopsysamplingcauseshematogenousdisseminationofepithelialcellularmaterial
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AT michaelhaggman prostatebiopsysamplingcauseshematogenousdisseminationofepithelialcellularmaterial
AT hanswiksell prostatebiopsysamplingcauseshematogenousdisseminationofepithelialcellularmaterial
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