Clinical characteristics and plasma exchange response in Guillain-Barré patients
The objective of the study was to describe the clinical characteristics, treatment response and possible associated factors of patients with Guillain-Barré syndrome at the National Institute of Neurological Sciences. A descriptive study on hospital discharges was conducted during the period 2017-201...
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doaj-2c38cc8653844851aae7a99a2e06134e2021-05-11T21:46:25ZspaInstituto Nacional de SaludRevista Peruana de Medicina Experimental y Salud Pública1726-46341726-46422021-03-01381899410.17843/rpmesp.2021.381.62332448Clinical characteristics and plasma exchange response in Guillain-Barré patientsErik Guevara-Silva0Sheila Castro-Suarez1César Caparó-Zamalloa2Jaqueline Cortez-Escalante3María Meza-Vega4Centro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Perú. Médico especialista en Neurología; doctor en MedicinaCentro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Perú. Atlantic Fellow for Equity in Brain Health at the University of California San Francisco, Department of Neurology, University of California San Francisco, CA, USA. Médico especialista en NeurologíaCentro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Perú. Médico especialista en NeurologíaCentro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Perú. Médico especialista en NeurologíaCentro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Perú. Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico especialista en Neurología magister en NeuropsicologíaThe objective of the study was to describe the clinical characteristics, treatment response and possible associated factors of patients with Guillain-Barré syndrome at the National Institute of Neurological Sciences. A descriptive study on hospital discharges was conducted during the period 2017-2019. Treatment response was evaluated based on Hughes’ disability scale. From 31 patients 61.3% were males and the mean age was 50 years. At admission, 87.1% of patients were on grade 3 or 4 of Hughes scale, most of them with axonal compromise which was associated to disability. Only 22 patients received plasma exchange; 6 months thereafter, 90.9% of patients decreased by at least one degree in Hughes scale and 42.8% were left without disability. In conclusion, a male and axonal subtype predominance was found, been the latter associated to disability.https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6233líquido cefalorraquídeoneuropatía axonalneuropatía desmielinizantepoliradiculoneuropatíaplasmaféresisperúrecambio plasmático terapéuticosíndrome de guillain-barré |
collection |
DOAJ |
language |
Spanish |
format |
Article |
sources |
DOAJ |
author |
Erik Guevara-Silva Sheila Castro-Suarez César Caparó-Zamalloa Jaqueline Cortez-Escalante María Meza-Vega |
spellingShingle |
Erik Guevara-Silva Sheila Castro-Suarez César Caparó-Zamalloa Jaqueline Cortez-Escalante María Meza-Vega Clinical characteristics and plasma exchange response in Guillain-Barré patients Revista Peruana de Medicina Experimental y Salud Pública líquido cefalorraquídeo neuropatía axonal neuropatía desmielinizante poliradiculoneuropatía plasmaféresis perú recambio plasmático terapéutico síndrome de guillain-barré |
author_facet |
Erik Guevara-Silva Sheila Castro-Suarez César Caparó-Zamalloa Jaqueline Cortez-Escalante María Meza-Vega |
author_sort |
Erik Guevara-Silva |
title |
Clinical characteristics and plasma exchange response in Guillain-Barré patients |
title_short |
Clinical characteristics and plasma exchange response in Guillain-Barré patients |
title_full |
Clinical characteristics and plasma exchange response in Guillain-Barré patients |
title_fullStr |
Clinical characteristics and plasma exchange response in Guillain-Barré patients |
title_full_unstemmed |
Clinical characteristics and plasma exchange response in Guillain-Barré patients |
title_sort |
clinical characteristics and plasma exchange response in guillain-barré patients |
publisher |
Instituto Nacional de Salud |
series |
Revista Peruana de Medicina Experimental y Salud Pública |
issn |
1726-4634 1726-4642 |
publishDate |
2021-03-01 |
description |
The objective of the study was to describe the clinical characteristics, treatment response and possible associated factors of patients with Guillain-Barré syndrome at the National Institute of Neurological Sciences. A descriptive study on hospital discharges was conducted during the period 2017-2019. Treatment response was evaluated based on Hughes’ disability scale. From 31 patients 61.3% were males and the mean age was 50 years. At admission, 87.1% of patients were on grade 3 or 4 of Hughes scale, most of them with axonal compromise which was associated to disability. Only 22 patients received plasma exchange; 6 months thereafter, 90.9% of patients decreased by at least one degree in Hughes scale and 42.8% were left without disability. In conclusion, a male and axonal subtype predominance was found, been the latter associated to disability. |
topic |
líquido cefalorraquídeo neuropatía axonal neuropatía desmielinizante poliradiculoneuropatía plasmaféresis perú recambio plasmático terapéutico síndrome de guillain-barré |
url |
https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6233 |
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1721443494178848768 |