Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice.

Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice.

Correlates of protection (CoP) are invaluable for iterative vaccine design studies, especially in pursuit of complex vaccines such as a universal influenza vaccine (UFV) where a single antigen is optimized to elicit broad protection against many viral antigenic variants. Since broadly protective ant...

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Bibliographic Details
Main Authors: Laurens P Kil, Joost Vaneman, Joan E M van der Lubbe, Dominika Czapska-Casey, Jeroen T B M Tolboom, Ramon Roozendaal, Roland C Zahn, Harmjan Kuipers, Laura Solforosi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225063

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