Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection.
Host protection from fungal infection is thought to ensue in part from the activity of Syk-coupled C-type lectin receptors and MyD88-coupled toll-like receptors in myeloid cells, including neutrophils, macrophages and dendritic cells (DCs). Given the multitude of cell types and receptors involved, e...
Main Authors: | Paul G Whitney, Eva Bär, Fabiola Osorio, Neil C Rogers, Barbara U Schraml, Safia Deddouche, Salomé LeibundGut-Landmann, Caetano Reis e Sousa |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4102599?pdf=render |
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