Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients

Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients

<p>Abstract</p> <p>Background</p> <p>Individuals with implanted mechanical valve prostheses require lifelong anticoagulation therapy with warfarin. The narrow therapeutic index of warfarin makes it difficult to dose and maintain proper anticoagulation. A number of singl...

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Bibliographic Details
Main Authors: Li Jie-Hui, Ma Guo-Guo, Zhu Shu-Qiang, Yan Hao, Wu Yong-Bing, Xu Jian-Jun
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Warfarin
CYP4F2
SNP
Valve
Implant
INR
Online Access:http://www.cardiothoracicsurgery.org/content/7/1/97

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