Targeted changes of the cell wall proteome influence Candida albicans ability to form single- and multi-strain biofilms.

Targeted changes of the cell wall proteome influence Candida albicans ability to form single- and multi-strain biofilms.

Biofilm formation is an important virulence trait of the pathogenic yeast Candida albicans. We have combined gene overexpression, strain barcoding and microarray profiling to screen a library of 531 C. albicans conditional overexpression strains (∼10% of the genome) for genes affecting biofilm devel...

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Bibliographic Details
Main Authors: Vitor Cabral, Sadri Znaidi, Louise A Walker, Hélène Martin-Yken, Etienne Dague, Mélanie Legrand, Keunsook Lee, Murielle Chauvel, Arnaud Firon, Tristan Rossignol, Mathias L Richard, Carol A Munro, Sophie Bachellier-Bassi, Christophe d'Enfert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4263760?pdf=render

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