Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle
Growth differentiation factor 8 (GDF8) or myostatin is a member of the transforming growth factor β (TGF-β) superfamily, which includes proteins that mediate key events in cell growth and development through signal transduction. In the absence of myostatin, the skeletal musculature...
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Taylor & Francis Group
2011-03-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://www.aspajournal.it/index.php/ijas/article/view/1951 |
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doaj-2c89218bcb1046a6ad2e868c8ac7fe2a2020-11-25T01:12:23ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2011-03-0121S646610.4081/ijas.2003.s1.64Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattleA. NardoneA. ValentiniF. FilippiniA. CrisàC. MarchitelliM.C. SavareseGrowth differentiation factor 8 (GDF8) or myostatin is a member of the transforming growth factor β (TGF-β) superfamily, which includes proteins that mediate key events in cell growth and development through signal transduction. In the absence of myostatin, the skeletal musculature of mice is two to three times greater in mass than that of wild-type mice (McPherron et al., 1997). Several cattle breeds are characterized by double muscling phenotype and GDF8 has been extensively investigated in cattle.A large number of variants have been identified in these species,most of which are silent or neutral.........http://www.aspajournal.it/index.php/ijas/article/view/1951double muscled, myostatin, linkage disequilibrium, allele age |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
A. Nardone A. Valentini F. Filippini A. Crisà C. Marchitelli M.C. Savarese |
| spellingShingle |
A. Nardone A. Valentini F. Filippini A. Crisà C. Marchitelli M.C. Savarese Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle Italian Journal of Animal Science double muscled, myostatin, linkage disequilibrium, allele age |
| author_facet |
A. Nardone A. Valentini F. Filippini A. Crisà C. Marchitelli M.C. Savarese |
| author_sort |
A. Nardone |
| title |
Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| title_short |
Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| title_full |
Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| title_fullStr |
Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| title_full_unstemmed |
Dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| title_sort |
dating the onset of some mutations in myostatin gene determining the double muscled phenotype in beef cattle |
| publisher |
Taylor & Francis Group |
| series |
Italian Journal of Animal Science |
| issn |
1594-4077 1828-051X |
| publishDate |
2011-03-01 |
| description |
Growth differentiation factor 8 (GDF8) or myostatin is a member of the transforming growth factor β (TGF-β) superfamily, which includes proteins that mediate key events in cell growth and development through signal transduction. In the absence of myostatin, the skeletal musculature of mice is two to three times greater in mass than that of wild-type mice (McPherron et al., 1997). Several cattle breeds are characterized by double muscling phenotype and GDF8 has been extensively investigated in cattle.A large number of variants have been identified in these species,most of which are silent or neutral......... |
| topic |
double muscled, myostatin, linkage disequilibrium, allele age |
| url |
http://www.aspajournal.it/index.php/ijas/article/view/1951 |
| work_keys_str_mv |
AT anardone datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle AT avalentini datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle AT ffilippini datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle AT acrisa datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle AT cmarchitelli datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle AT mcsavarese datingtheonsetofsomemutationsinmyostatingenedeterminingthedoublemuscledphenotypeinbeefcattle |
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1725166749837426688 |