Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy
Aim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therap...
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Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1627 |
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doaj-2cbe432d2aa84c3d85ec10d96bb6505d2021-07-28T13:50:48Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-12-017617201344Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapyM. V. Lozhakova0Nizhniy Novgorod State Medical Academy. Nizhniy NovgorodAim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therapy (10 mg once a day), all participants underwent 24-hour blood pressure monitoring (BPM), peripheral hemodynamics and MC assessment.Results. Eight-week bisoprolol therapy (10 mg/d) was associated with target BP level achievement in 74% of the patients. In 76%, circadian BP profile had been normalized. Bisoprolol treatment also improved peripheral hemodynamics and MC parameters. Significant reduction in total peripheral vascular resistance and pulse wave velocity was observed in 95%, normalization of these parameters - in 54%. MC parameters normalized in 67% and improved in 94%.Conclusion. Bisoprolol demonstrated high antihypertensive activity and beneficial effects on peripheral hemodynamics and MC parameters.https://cardiovascular.elpub.ru/jour/article/view/1627bisoprolol24-hour blood pressure monitoringperipheral hemodynamics parametersmicrocirculation |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
M. V. Lozhakova |
spellingShingle |
M. V. Lozhakova Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy Кардиоваскулярная терапия и профилактика bisoprolol 24-hour blood pressure monitoring peripheral hemodynamics parameters microcirculation |
author_facet |
M. V. Lozhakova |
author_sort |
M. V. Lozhakova |
title |
Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
title_short |
Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
title_full |
Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
title_fullStr |
Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
title_full_unstemmed |
Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
title_sort |
peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
publisher |
«SILICEA-POLIGRAF» LLC |
series |
Кардиоваскулярная терапия и профилактика |
issn |
1728-8800 2619-0125 |
publishDate |
2008-12-01 |
description |
Aim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therapy (10 mg once a day), all participants underwent 24-hour blood pressure monitoring (BPM), peripheral hemodynamics and MC assessment.Results. Eight-week bisoprolol therapy (10 mg/d) was associated with target BP level achievement in 74% of the patients. In 76%, circadian BP profile had been normalized. Bisoprolol treatment also improved peripheral hemodynamics and MC parameters. Significant reduction in total peripheral vascular resistance and pulse wave velocity was observed in 95%, normalization of these parameters - in 54%. MC parameters normalized in 67% and improved in 94%.Conclusion. Bisoprolol demonstrated high antihypertensive activity and beneficial effects on peripheral hemodynamics and MC parameters. |
topic |
bisoprolol 24-hour blood pressure monitoring peripheral hemodynamics parameters microcirculation |
url |
https://cardiovascular.elpub.ru/jour/article/view/1627 |
work_keys_str_mv |
AT mvlozhakova peripheralhemodynamicsandmicrocirculationdynamicsinarterialhypertensionpatientsreceivingbisoprololmonotherapy |
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1721271207300431872 |