An Overview of The Globozoospermia as A Multigenic Identified Syndrome

An Overview of The Globozoospermia as A Multigenic Identified Syndrome

Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome b...

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Bibliographic Details
Main Authors: Parastoo Modarres, Marziyeh Tavalaee, Kamran Ghaedi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2019-01-01
Series:International Journal of Fertility and Sterility
Subjects:
acrosome
globozoospermia
male infertility
Online Access:http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdf
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spelling doaj-2cc0c9fe3fd24082a97e535ff8bb7eee2020-11-25T04:08:20ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782019-01-0112427327710.22074/ijfs.2019.556145502An Overview of The Globozoospermia as A Multigenic Identified SyndromeParastoo Modarres0Marziyeh Tavalaee1Kamran Ghaedi2Department of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran;Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, IraDepartment of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, IranDepartment of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran;Department of Cellular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, IranAcrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-golgi network (TGN), acroplaxome and cellular trafficking. This review aims to explain roles of related signals and molecules involved in this process and also describe how their absence in form of mutation, deletion and knockout model may lead to phe- nomenon referred to globozoospermia.http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdfacrosomeglobozoospermiamale infertility
collection DOAJ
language English
format Article
sources DOAJ
author Parastoo Modarres
Marziyeh Tavalaee
Kamran Ghaedi
spellingShingle Parastoo Modarres
Marziyeh Tavalaee
Kamran Ghaedi
An Overview of The Globozoospermia as A Multigenic Identified Syndrome
International Journal of Fertility and Sterility
acrosome
globozoospermia
male infertility
author_facet Parastoo Modarres
Marziyeh Tavalaee
Kamran Ghaedi
author_sort Parastoo Modarres
title An Overview of The Globozoospermia as A Multigenic Identified Syndrome
title_short An Overview of The Globozoospermia as A Multigenic Identified Syndrome
title_full An Overview of The Globozoospermia as A Multigenic Identified Syndrome
title_fullStr An Overview of The Globozoospermia as A Multigenic Identified Syndrome
title_full_unstemmed An Overview of The Globozoospermia as A Multigenic Identified Syndrome
title_sort overview of the globozoospermia as a multigenic identified syndrome
publisher Royan Institute (ACECR), Tehran
series International Journal of Fertility and Sterility
issn 2008-076X
2008-0778
publishDate 2019-01-01
description Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-golgi network (TGN), acroplaxome and cellular trafficking. This review aims to explain roles of related signals and molecules involved in this process and also describe how their absence in form of mutation, deletion and knockout model may lead to phe- nomenon referred to globozoospermia.
topic acrosome
globozoospermia
male infertility
url http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdf
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