An Overview of The Globozoospermia as A Multigenic Identified Syndrome
Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome b...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2019-01-01
|
Series: | International Journal of Fertility and Sterility |
Subjects: | |
Online Access: | http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdf |
id |
doaj-2cc0c9fe3fd24082a97e535ff8bb7eee |
---|---|
record_format |
Article |
spelling |
doaj-2cc0c9fe3fd24082a97e535ff8bb7eee2020-11-25T04:08:20ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782019-01-0112427327710.22074/ijfs.2019.556145502An Overview of The Globozoospermia as A Multigenic Identified SyndromeParastoo Modarres0Marziyeh Tavalaee1Kamran Ghaedi2Department of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran;Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, IraDepartment of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, IranDepartment of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran;Department of Cellular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, IranAcrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-golgi network (TGN), acroplaxome and cellular trafficking. This review aims to explain roles of related signals and molecules involved in this process and also describe how their absence in form of mutation, deletion and knockout model may lead to phe- nomenon referred to globozoospermia.http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdfacrosomeglobozoospermiamale infertility |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Parastoo Modarres Marziyeh Tavalaee Kamran Ghaedi |
spellingShingle |
Parastoo Modarres Marziyeh Tavalaee Kamran Ghaedi An Overview of The Globozoospermia as A Multigenic Identified Syndrome International Journal of Fertility and Sterility acrosome globozoospermia male infertility |
author_facet |
Parastoo Modarres Marziyeh Tavalaee Kamran Ghaedi |
author_sort |
Parastoo Modarres |
title |
An Overview of The Globozoospermia as A Multigenic Identified Syndrome |
title_short |
An Overview of The Globozoospermia as A Multigenic Identified Syndrome |
title_full |
An Overview of The Globozoospermia as A Multigenic Identified Syndrome |
title_fullStr |
An Overview of The Globozoospermia as A Multigenic Identified Syndrome |
title_full_unstemmed |
An Overview of The Globozoospermia as A Multigenic Identified Syndrome |
title_sort |
overview of the globozoospermia as a multigenic identified syndrome |
publisher |
Royan Institute (ACECR), Tehran |
series |
International Journal of Fertility and Sterility |
issn |
2008-076X 2008-0778 |
publishDate |
2019-01-01 |
description |
Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-golgi network (TGN), acroplaxome and cellular trafficking. This review aims to explain roles of related signals and molecules involved in this process and also describe how their absence in form of mutation, deletion and knockout model may lead to phe- nomenon referred to globozoospermia. |
topic |
acrosome globozoospermia male infertility |
url |
http://www.ijfs.ir/article_45502_0fb5fca1ce7ed6d030e7af33e1b275dc.pdf |
work_keys_str_mv |
AT parastoomodarres anoverviewoftheglobozoospermiaasamultigenicidentifiedsyndrome AT marziyehtavalaee anoverviewoftheglobozoospermiaasamultigenicidentifiedsyndrome AT kamranghaedi anoverviewoftheglobozoospermiaasamultigenicidentifiedsyndrome AT parastoomodarres overviewoftheglobozoospermiaasamultigenicidentifiedsyndrome AT marziyehtavalaee overviewoftheglobozoospermiaasamultigenicidentifiedsyndrome AT kamranghaedi overviewoftheglobozoospermiaasamultigenicidentifiedsyndrome |
_version_ |
1724426280140537856 |