Hereditary syndromes associated with the congenital heart diseases in Azerbaijan
This article is devoted to the study of the incidence and structure of the genetic syndromes associated with congenital heart diseases in Azerbaijan. The results of observation of 430 children with congenital heart diseases, which have been stayed in the Child Department of Scientific Surgery Center...
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Ltd. “The National Academy of Pediatric Science and Innovation”
2018-03-01
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doaj-2cd306f0e89f4c73868f055408ce366c2021-07-28T16:27:48ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282018-03-01631788010.21508/1027-4065-2018-63-1-78-80552Hereditary syndromes associated with the congenital heart diseases in AzerbaijanN. A. Gadzhieva0Azerbaijan Medical University, BakuThis article is devoted to the study of the incidence and structure of the genetic syndromes associated with congenital heart diseases in Azerbaijan. The results of observation of 430 children with congenital heart diseases, which have been stayed in the Child Department of Scientific Surgery Center named after Academician M.A. Topchubashov during 2010-2015 period, have been analyzed. It was demonstrated that the incidence of the chromosomal and monogenic pathological conditions is 6.5±1.2% (28 children) among the above population. The chromosomal syndromes were diagnosed in 20 (4.7±1.0%) children, monogenic ones – in 8 (1.9+0.7%) children. The chromosomal pathological condition was mostly presented with the Down’s syndrome (in 12 patents). As to the monogenic syndromes, it was mostly the heterotoxic syndrome (4 children). These data testify that in spite of the multifactorial genesis of the most of the congenital heart diseases and role of the unfavorable factors of the antenatal period, the genetic component influences with a great importance upon the prevalence rate of the malformations.https://www.ped-perinatology.ru/jour/article/view/623childrencongenital heart diseasechromosomal pathological conditiondown’s syndromemonogenic syndromesheterotoxic syndrome |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
N. A. Gadzhieva |
spellingShingle |
N. A. Gadzhieva Hereditary syndromes associated with the congenital heart diseases in Azerbaijan Rossijskij Vestnik Perinatologii i Pediatrii children congenital heart disease chromosomal pathological condition down’s syndrome monogenic syndromes heterotoxic syndrome |
author_facet |
N. A. Gadzhieva |
author_sort |
N. A. Gadzhieva |
title |
Hereditary syndromes associated with the congenital heart diseases in Azerbaijan |
title_short |
Hereditary syndromes associated with the congenital heart diseases in Azerbaijan |
title_full |
Hereditary syndromes associated with the congenital heart diseases in Azerbaijan |
title_fullStr |
Hereditary syndromes associated with the congenital heart diseases in Azerbaijan |
title_full_unstemmed |
Hereditary syndromes associated with the congenital heart diseases in Azerbaijan |
title_sort |
hereditary syndromes associated with the congenital heart diseases in azerbaijan |
publisher |
Ltd. “The National Academy of Pediatric Science and Innovation” |
series |
Rossijskij Vestnik Perinatologii i Pediatrii |
issn |
1027-4065 2500-2228 |
publishDate |
2018-03-01 |
description |
This article is devoted to the study of the incidence and structure of the genetic syndromes associated with congenital heart diseases in Azerbaijan. The results of observation of 430 children with congenital heart diseases, which have been stayed in the Child Department of Scientific Surgery Center named after Academician M.A. Topchubashov during 2010-2015 period, have been analyzed. It was demonstrated that the incidence of the chromosomal and monogenic pathological conditions is 6.5±1.2% (28 children) among the above population. The chromosomal syndromes were diagnosed in 20 (4.7±1.0%) children, monogenic ones – in 8 (1.9+0.7%) children. The chromosomal pathological condition was mostly presented with the Down’s syndrome (in 12 patents). As to the monogenic syndromes, it was mostly the heterotoxic syndrome (4 children). These data testify that in spite of the multifactorial genesis of the most of the congenital heart diseases and role of the unfavorable factors of the antenatal period, the genetic component influences with a great importance upon the prevalence rate of the malformations. |
topic |
children congenital heart disease chromosomal pathological condition down’s syndrome monogenic syndromes heterotoxic syndrome |
url |
https://www.ped-perinatology.ru/jour/article/view/623 |
work_keys_str_mv |
AT nagadzhieva hereditarysyndromesassociatedwiththecongenitalheartdiseasesinazerbaijan |
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1721266276327751680 |