Interplay between Gating and Block of Ligand-Gated Ion Channels

Interplay between Gating and Block of Ligand-Gated Ion Channels

Drugs that inhibit ion channel function by binding in the channel and preventing current flow, known as channel blockers, can be used as powerful tools for analysis of channel properties. Channel blockers are used to probe both the sophisticated structure and basic biophysical properties of ion chan...

Full description

Bibliographic Details
Main Authors: Matthew B. Phillips, Aparna Nigam, Jon W. Johnson
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Brain Sciences
Subjects:
ligand-gated ion channel
channel block
channel gating
nicotinic acetylcholine receptor
ionotropic glutamate receptor
AMPA receptor
Online Access:https://www.mdpi.com/2076-3425/10/12/928

Similar Items

Similar Items