Chicken IgY Fc linked to Bordetella avium ompA and Taishan Pinus massoniana pollen polysaccharide adjuvant enhances macrophage function and specific immune responses

Chicken IgY Fc linked to Bordetella avium ompA and Taishan Pinus massoniana pollen polysaccharide adjuvant enhances macrophage function and specific immune responses

Fc-fusion technologies, in which immunoglobulin Fc is genetically fused to an antigenic protein, have been developed to confer antibody-like properties to proteins and peptides. Mammalian IgG Fc fusion exhibits improved antigen-induced immune responses by providing aggregates with high avidity for t...

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Bibliographic Details
Main Authors: Zhu Ruiliang, Kai Wei, Wenwen Dong, Hao Zhang, He Huang, Jianbo Zhou, Liping Hu, Ailing Lian, Lijun Zhu, Ningning Ma, Pingping Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Microbiology
Subjects:
subunit vaccine
Peritoneal macrophage
Pichia pastoris expression
TPPPS
IgY Fc
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01708/full

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