Molecular Design of Microcapsule Shells for Visible Light-Triggered Release
The development of photo-responsive capsules to tune and control the sustained-release of encapsulated actives is a fascinating and challenging route to improve the performances and effectiveness of a wide range of delivery applications. In this work, we report the preparation of visible light-respo...
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doaj-2ce8de93759043749007d6b6529e2e482020-11-25T01:17:52ZengMDPI AGPolymers2073-43602019-05-0111590410.3390/polym11050904polym11050904Molecular Design of Microcapsule Shells for Visible Light-Triggered ReleaseDomenico Pirone0Valentina Marturano1Rita Del Pezzo2Susana Fernández Prieto3Todd Underiner4Marta Giamberini5Bartosz Tylkowski6Department of Chemical Engineering, Rovira i Virgili University, Av. Països Catalans 26, 43007 Tarragona, SpainDepartment of Chemical, Materials, and Production Engineering (DICMAPI), University of Naples “Federico II”, P. le Tecchio, 80, 80125 Napoli, ItalyDepartment of Chemical Engineering, Rovira i Virgili University, Av. Països Catalans 26, 43007 Tarragona, SpainProcter & Gamble Services Company n.v., Temselaan 100, 1853 Strombeek-Bever, BelgiumThe Procter and Gamble Company, 6210 Center Hill Avenue, Cincinnati, OH 45224, USADepartment of Chemical Engineering, Rovira i Virgili University, Av. Països Catalans 26, 43007 Tarragona, SpainDepartment of Chemical Engineering, Rovira i Virgili University, Av. Països Catalans 26, 43007 Tarragona, SpainThe development of photo-responsive capsules to tune and control the sustained-release of encapsulated actives is a fascinating and challenging route to improve the performances and effectiveness of a wide range of delivery applications. In this work, we report the preparation of visible light-responsive capsules obtained via oil-in-water interfacial polycondensation between modified diacyl-chloride azobenzene moiety and diamine flexible spacer in the presence of cross-linkers with different structures and functionalities. The effect on the release profile of the encapsulated perfume oil was investigated using three flexible spacers with different lengths (1,8-diaminooctane; 1,6-diaminohexane and 1,4-diaminobutane) and two types of cross-linkers (1,3,5-benzenetricarbonyl trichloride and melamine). We analyzed how the properties of microcapsules can be tailored changing the design of the shell structure. Fine tuning of the perfume release profiles was obtained. The changes in capsules size and morphology due to visible light irradiation were monitored via light scattering, optical microscopy and atomic force microscopy. Perfume release was 50% faster in the systems prepared with melamine as the cross-linker. Modelling studies were carried out to support the discussion of the experimental results.https://www.mdpi.com/2073-4360/11/5/904encapsulationphoto-triggered releasemodified azobenzene |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Domenico Pirone Valentina Marturano Rita Del Pezzo Susana Fernández Prieto Todd Underiner Marta Giamberini Bartosz Tylkowski |
spellingShingle |
Domenico Pirone Valentina Marturano Rita Del Pezzo Susana Fernández Prieto Todd Underiner Marta Giamberini Bartosz Tylkowski Molecular Design of Microcapsule Shells for Visible Light-Triggered Release Polymers encapsulation photo-triggered release modified azobenzene |
author_facet |
Domenico Pirone Valentina Marturano Rita Del Pezzo Susana Fernández Prieto Todd Underiner Marta Giamberini Bartosz Tylkowski |
author_sort |
Domenico Pirone |
title |
Molecular Design of Microcapsule Shells for Visible Light-Triggered Release |
title_short |
Molecular Design of Microcapsule Shells for Visible Light-Triggered Release |
title_full |
Molecular Design of Microcapsule Shells for Visible Light-Triggered Release |
title_fullStr |
Molecular Design of Microcapsule Shells for Visible Light-Triggered Release |
title_full_unstemmed |
Molecular Design of Microcapsule Shells for Visible Light-Triggered Release |
title_sort |
molecular design of microcapsule shells for visible light-triggered release |
publisher |
MDPI AG |
series |
Polymers |
issn |
2073-4360 |
publishDate |
2019-05-01 |
description |
The development of photo-responsive capsules to tune and control the sustained-release of encapsulated actives is a fascinating and challenging route to improve the performances and effectiveness of a wide range of delivery applications. In this work, we report the preparation of visible light-responsive capsules obtained via oil-in-water interfacial polycondensation between modified diacyl-chloride azobenzene moiety and diamine flexible spacer in the presence of cross-linkers with different structures and functionalities. The effect on the release profile of the encapsulated perfume oil was investigated using three flexible spacers with different lengths (1,8-diaminooctane; 1,6-diaminohexane and 1,4-diaminobutane) and two types of cross-linkers (1,3,5-benzenetricarbonyl trichloride and melamine). We analyzed how the properties of microcapsules can be tailored changing the design of the shell structure. Fine tuning of the perfume release profiles was obtained. The changes in capsules size and morphology due to visible light irradiation were monitored via light scattering, optical microscopy and atomic force microscopy. Perfume release was 50% faster in the systems prepared with melamine as the cross-linker. Modelling studies were carried out to support the discussion of the experimental results. |
topic |
encapsulation photo-triggered release modified azobenzene |
url |
https://www.mdpi.com/2073-4360/11/5/904 |
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