Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

Squamous cell carcinoma (SCC) of the lung is the second most common subtype of lung cancer. With limited treatment options, the 5-year survival rate of SCC is only 15%. Although genomic alterations in SCC have been characterized, identifying the alterations that drive SCC is critical for improving t...

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Bibliographic Details
Main Authors: Anandaroop Mukhopadhyay, Kristofer C. Berrett, Ushma Kc, Phillip M. Clair, Stelian M. Pop, Shamus R. Carr, Benjamin L. Witt, Trudy G. Oliver
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714004306

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