Structural Consequences of Copper Binding to the Prion Protein

Structural Consequences of Copper Binding to the Prion Protein

Prion, or PrP<sup>Sc</sup>, is the pathological isoform of the cellular prion protein (PrP<sup>C</sup>) and it is the etiological agent of transmissible spongiform encephalopathies (TSE) affecting humans and animal species. The most relevant function of PrP<sup>C</su...

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Bibliographic Details
Main Authors:	Giulia Salzano, Gabriele Giachin, Giuseppe Legname
Format:	Article
Language:	English
Published:	MDPI AG 2019-07-01
Series:	Cells
Subjects:	prion protein copper binding copper coordination geometries neurodegenerative diseases
Online Access:	https://www.mdpi.com/2073-4409/8/8/770

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