Immune-mediated liver failure
The primary causative factors of liver failure include direct damage and immune-mediated liver injury. Increasing evidence suggests that immune-mediated injury plays a pivotal role in the pathogenesis of liver failure. The new concepts concerning the mechanisms of immune-mediated liver injury in liv...
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Editorial Department of Journal of Clinical Hepatology
2014-10-01
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| Series: | Linchuang Gandanbing Zazhi |
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| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=6077&ClassID=912173216 |
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doaj-2cf4ce7f03984f1b9467bc966289c9d22020-11-24T23:27:04ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562014-10-01301098499110.3969/j.issn.1001-5256.2014.10.004Immune-mediated liver failureWANG Xiaojing0Department of Infectious Diseases, Tongji Hospital, Huazhong University of Science and Technology Tongji Medical College, Wuhan 430030, ChinaThe primary causative factors of liver failure include direct damage and immune-mediated liver injury. Increasing evidence suggests that immune-mediated injury plays a pivotal role in the pathogenesis of liver failure. The new concepts concerning the mechanisms of immune-mediated liver injury in liver failure are reviewed with relevant basic and clinical studies in both humans and animals. The innate and adaptive immunity, particularly the interaction of various immune cells and molecules, as well as apoptosis-related molecules, are discussed in detail. http://www.lcgdbzz.org/qk_content.asp?id=6077&ClassID=912173216liver failure; immunitynatural; immunityactive; cytokines; death domain receptor signaling adaptor proteins |
| collection |
DOAJ |
| language |
zho |
| format |
Article |
| sources |
DOAJ |
| author |
WANG Xiaojing |
| spellingShingle |
WANG Xiaojing Immune-mediated liver failure Linchuang Gandanbing Zazhi liver failure; immunity natural; immunity active; cytokines; death domain receptor signaling adaptor proteins |
| author_facet |
WANG Xiaojing |
| author_sort |
WANG Xiaojing |
| title |
Immune-mediated liver failure |
| title_short |
Immune-mediated liver failure |
| title_full |
Immune-mediated liver failure |
| title_fullStr |
Immune-mediated liver failure |
| title_full_unstemmed |
Immune-mediated liver failure |
| title_sort |
immune-mediated liver failure |
| publisher |
Editorial Department of Journal of Clinical Hepatology |
| series |
Linchuang Gandanbing Zazhi |
| issn |
1001-5256 1001-5256 |
| publishDate |
2014-10-01 |
| description |
The primary causative factors of liver failure include direct damage and immune-mediated liver injury. Increasing evidence suggests that immune-mediated injury plays a pivotal role in the pathogenesis of liver failure. The new concepts concerning the mechanisms of immune-mediated liver injury in liver failure are reviewed with relevant basic and clinical studies in both humans and animals. The innate and adaptive immunity, particularly the interaction of various immune cells and molecules, as well as apoptosis-related molecules, are discussed in detail.
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| topic |
liver failure; immunity natural; immunity active; cytokines; death domain receptor signaling adaptor proteins |
| url |
http://www.lcgdbzz.org/qk_content.asp?id=6077&ClassID=912173216 |
| work_keys_str_mv |
AT wangxiaojing immunemediatedliverfailure |
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