Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases.
As one of the largest protein families, protein kinases (PKs) regulate nearly all processes within the cell and are considered important drug targets. Much research has been conducted on inhibitors for PKs, leading to a wealth of compounds that target PKs that have potential to be lead anthelmintic...
Main Authors: | Christina M Taylor, John Martin, Ramakrishna U Rao, Kerrie Powell, Sahar Abubucker, Makedonka Mitreva |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-02-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3573124?pdf=render |
Similar Items
-
Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways.
by: Christina M Taylor, et al.
Published: (2013-01-01) -
Broad spectrum anthelmintic potential of Cassia plants
by: Suman Kundu, et al.
Published: (2014-05-01) -
HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization.
by: Sahar Abubucker, et al.
Published: (2011-01-01) -
Impact of broad-spectrum anthelmintic treatment in the summer on the weight gain of reindeer calves
by: A. Oksanen, et al.
Published: (1996-01-01) -
EFFICACY OF NEW BROAD SPECTRUM ANTHELMINTIC DRUGS FOR TREATMENT OF HELMINTHOSIS IN CATTLE IN CONDITIONS OF VOLOGDA REGION
by: A. L. Kryazhev, et al.
Published: (2016-05-01)