Intestinal Epithelial Serum Amyloid A Modulates Bacterial Growth In Vitro and Pro-Inflammatory Responses in Mouse Experimental Colitis

Intestinal Epithelial Serum Amyloid A Modulates Bacterial Growth In Vitro and Pro-Inflammatory Responses in Mouse Experimental Colitis

<p>Abstract</p> <p>Background</p> <p>Serum Amyloid A (SAA) is a major acute phase protein of unknown function. SAA is mostly expressed in the liver, but also in other tissues including the intestinal epithelium. SAA reportedly has anti-bacterial effects, and because inf...

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Main Authors: Wang Yu, Arsenescu Violeta, Arsenescu Razvan, Zhong Jian, Witta Jassir, Eckhardt Erik RM, Ghoshal Sarbani, de Beer Marcielle C, de Beer Frederick C, de Villiers Willem JS
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/10/133

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