The Use of Toll-Like Receptor Agonists in HIV-1 Cure Strategies

The Use of Toll-Like Receptor Agonists in HIV-1 Cure Strategies

Toll-like receptors (TLRs) are a family of pattern recognition receptors and part of the first line of defense against invading microbes. In humans, we know of 10 different TLRs, which are expressed to varying degrees in immune cell subsets. Engaging TLRs through their specific ligands leads to acti...

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Bibliographic Details
Main Authors: Janne Tegder Martinsen, Jesper Damsgaard Gunst, Jesper Falkesgaard Højen, Martin Tolstrup, Ole Schmeltz Søgaard
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
HIV-1
TLR
innate immunity
HIV-1 cure
HIV-1 vaccine
latency reversing agents
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01112/full

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