Enrichment Strategy for Systemic Sclerosis Clinical Trials Targeting Skin Fibrosis: A Prospective, Multiethnic Cohort Study
Objective The modified Rodnan skin score (mRSS) is often used as a primary outcome measure in systemic sclerosis (SSc) randomized clinical trials (RCTs). Previous cohort studies with predominantly European Caucasian patients showed that setting an upper limit of mRSS as a selection criterion for RCT...
Main Authors: | Carina Mihai, Rucsandra Dobrota, Shervin Assassi, Maureen D. Mayes, Oliver Distler |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-08-01
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Series: | ACR Open Rheumatology |
Online Access: | https://doi.org/10.1002/acr2.11165 |
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