The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance
Christian R Osadnik,1–4,* Matthias Loeckx,1,5,6,* Zafeiris Louvaris,1,7 Heleen Demeyer,1,6 Daniel Langer,1,6 Fernanda M Rodrigues,1,6 Wim Janssens,6,8 Ioannis Vogiatzis,7,9 Thierry Troosters1,6 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 2Department of Physiotherap...
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doaj-2d414bf50b5b4416ad04ffc9d7649d332020-11-25T00:40:16ZengDove Medical PressInternational Journal of COPD1178-20052018-10-01Volume 133515352741739The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise toleranceOsadnik CRLoeckx MLouvaris ZDemeyer HLanger DRodrigues FMJanssens WVogiatzis ITroosters TChristian R Osadnik,1–4,* Matthias Loeckx,1,5,6,* Zafeiris Louvaris,1,7 Heleen Demeyer,1,6 Daniel Langer,1,6 Fernanda M Rodrigues,1,6 Wim Janssens,6,8 Ioannis Vogiatzis,7,9 Thierry Troosters1,6 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 2Department of Physiotherapy, Monash University, Melbourne, Victoria, Australia; 3Monash Lung and Sleep, Monash Health, Melbourne, Victoria, Australia; 4Institute for Breathing and Sleep, Melbourne, Victoria, Australia; 5Department of Physiotherapy, LUNEX International University of Health, Exercise and Sports, Differdange, Luxembourg; 6Respiratory Division, University Hospitals, KU Leuven, Leuven, Belgium; 7Faculty of Physical Education and Sports Sciences, National and Kapodistrian University of Athens, Athens, Greece; 8Department of Chronic Disease, Metabolism and Aging, KU Leuven, Leuven, Belgium; 9Department of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK *These authors contributed equally to this work Purpose: Pulmonary rehabilitation (PR) enhances exercise tolerance in patients with COPD; however, improvements in physical activity (PA) are not guaranteed. This study explored the relationship between baseline exercise tolerance and changes in PA after PR.Materials and methods: Patient data from prospective clinical trials in the PR settings of Athens and Leuven (2008–2016) were analyzed. Validated PA monitors were worn for 1 week before and after a 12-week program. The proportion of patients who improved PA levels ≥1,000 steps/day (“PA responders”) after PR was compared between those with initial 6-minute walk distance [6MWDi] <350 m and ≥350 m. Baseline predictors of PA change were evaluated via univariate and multivariate logistic regression analyses.Results: Two hundred thirty-six patients with COPD (median [IQR] FEV1 44 [33–59] % predicted, age 65±8 years, 6MWDi 416 [332–486] m) were included. The proportion of “PA responders” after PR was significantly greater in those with higher vs lower 6MWDi (37.9% vs 16.4%, respectively; P<0.001). 6MWDi group classification was the strongest baseline independent predictor of PA improvement (univariate OR 3.10, 95% CI 1.51–6.36).Conclusion: The likelihood of improving PA after PR is increased with greater 6MWDi. Baseline exercise tolerance appears as an important stratification metric for future research in this field. Keywords: exercise and pulmonary rehabilitation, COPD, physical activity, clinical respiratory medicine, responder analysishttps://www.dovepress.com/the-likelihood-of-improving-physical-activity-after-pulmonary-rehabili-peer-reviewed-article-COPDExercise and Pulmonary RehabilitationCOPDPhysical activityClinical Respiratory Medicine |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Osadnik CR Loeckx M Louvaris Z Demeyer H Langer D Rodrigues FM Janssens W Vogiatzis I Troosters T |
spellingShingle |
Osadnik CR Loeckx M Louvaris Z Demeyer H Langer D Rodrigues FM Janssens W Vogiatzis I Troosters T The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance International Journal of COPD Exercise and Pulmonary Rehabilitation COPD Physical activity Clinical Respiratory Medicine |
author_facet |
Osadnik CR Loeckx M Louvaris Z Demeyer H Langer D Rodrigues FM Janssens W Vogiatzis I Troosters T |
author_sort |
Osadnik CR |
title |
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance |
title_short |
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance |
title_full |
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance |
title_fullStr |
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance |
title_full_unstemmed |
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance |
title_sort |
likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with copd who have better exercise tolerance |
publisher |
Dove Medical Press |
series |
International Journal of COPD |
issn |
1178-2005 |
publishDate |
2018-10-01 |
description |
Christian R Osadnik,1–4,* Matthias Loeckx,1,5,6,* Zafeiris Louvaris,1,7 Heleen Demeyer,1,6 Daniel Langer,1,6 Fernanda M Rodrigues,1,6 Wim Janssens,6,8 Ioannis Vogiatzis,7,9 Thierry Troosters1,6 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 2Department of Physiotherapy, Monash University, Melbourne, Victoria, Australia; 3Monash Lung and Sleep, Monash Health, Melbourne, Victoria, Australia; 4Institute for Breathing and Sleep, Melbourne, Victoria, Australia; 5Department of Physiotherapy, LUNEX International University of Health, Exercise and Sports, Differdange, Luxembourg; 6Respiratory Division, University Hospitals, KU Leuven, Leuven, Belgium; 7Faculty of Physical Education and Sports Sciences, National and Kapodistrian University of Athens, Athens, Greece; 8Department of Chronic Disease, Metabolism and Aging, KU Leuven, Leuven, Belgium; 9Department of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK *These authors contributed equally to this work Purpose: Pulmonary rehabilitation (PR) enhances exercise tolerance in patients with COPD; however, improvements in physical activity (PA) are not guaranteed. This study explored the relationship between baseline exercise tolerance and changes in PA after PR.Materials and methods: Patient data from prospective clinical trials in the PR settings of Athens and Leuven (2008–2016) were analyzed. Validated PA monitors were worn for 1 week before and after a 12-week program. The proportion of patients who improved PA levels ≥1,000 steps/day (“PA responders”) after PR was compared between those with initial 6-minute walk distance [6MWDi] <350 m and ≥350 m. Baseline predictors of PA change were evaluated via univariate and multivariate logistic regression analyses.Results: Two hundred thirty-six patients with COPD (median [IQR] FEV1 44 [33–59] % predicted, age 65±8 years, 6MWDi 416 [332–486] m) were included. The proportion of “PA responders” after PR was significantly greater in those with higher vs lower 6MWDi (37.9% vs 16.4%, respectively; P<0.001). 6MWDi group classification was the strongest baseline independent predictor of PA improvement (univariate OR 3.10, 95% CI 1.51–6.36).Conclusion: The likelihood of improving PA after PR is increased with greater 6MWDi. Baseline exercise tolerance appears as an important stratification metric for future research in this field. Keywords: exercise and pulmonary rehabilitation, COPD, physical activity, clinical respiratory medicine, responder analysis |
topic |
Exercise and Pulmonary Rehabilitation COPD Physical activity Clinical Respiratory Medicine |
url |
https://www.dovepress.com/the-likelihood-of-improving-physical-activity-after-pulmonary-rehabili-peer-reviewed-article-COPD |
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