DNA damage induced by cis- and carboplatin as indicator for in vitro sensitivity of ovarian carcinoma cells

<p>Abstract</p> <p>Background</p> <p>The DNA damage by platinum cytostatics is thought to be the main cause of their cytotoxicity. Therefore the measurement of the DNA damage induced by cis- and carboplatin should reflect the sensitivity of cancer cells toward the plati...

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Bibliographic Details
Main Authors: de Wilde Rudy L, Tchartchian Garri, Klasen Hermann A, Unger Florian T, Witte Irene
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/359

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