Towards Unraveling the Histone Code by Fragment Blind Docking

Histones serve as protein spools for winding the DNA in the nucleosome. High variability of their post-translational modifications result in a unique code system often responsible for the pathomechanisms of epigenetics-based diseases. Decoding is performed by reader proteins via complex formation wi...

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Bibliographic Details
Main Authors: Mónika Bálint, István Horváth, Nikolett Mészáros, Csaba Hetényi
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/20/2/422