Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obesity) on the expression of DMEs have not been eluci...
Main Authors: | Pei Wang, Xueyan Shao, Yifan Bao, Junjie Zhu, Liming Chen, Lirong Zhang, Xiaochao Ma, Xiao-bo Zhong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Acta Pharmaceutica Sinica B |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383519308585 |
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