Agentes dopaminérgicos e o tratamento da disfunção erétil
The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopam...
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Sociedade Brasileira de Química
2004-01-01
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020 |
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doaj-2d8e243dc7c34fbd846eed0d5292b5fc2020-11-24T23:15:04ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642004-01-01276949957Agentes dopaminérgicos e o tratamento da disfunção erétilNeves GildaRates Stela M. K.Fraga Carlos A. M.Barreiro Eliezer J.The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopaminergic agents to elicit penile erection has been described since 1975 and successively confirmed by numerous studies. The development of apomorphine SL (dopaminergic non selective agonist) to enhance erectile function represents a new pharmacological approach to the management of erectile dysfunction using CNS drugs. The search for selective D4 dopaminergic agents is being explored by some research groups and pharmaceutical companies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020erectile dysfunctiondopaminergic agentsapomorphine |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Neves Gilda Rates Stela M. K. Fraga Carlos A. M. Barreiro Eliezer J. |
spellingShingle |
Neves Gilda Rates Stela M. K. Fraga Carlos A. M. Barreiro Eliezer J. Agentes dopaminérgicos e o tratamento da disfunção erétil Química Nova erectile dysfunction dopaminergic agents apomorphine |
author_facet |
Neves Gilda Rates Stela M. K. Fraga Carlos A. M. Barreiro Eliezer J. |
author_sort |
Neves Gilda |
title |
Agentes dopaminérgicos e o tratamento da disfunção erétil |
title_short |
Agentes dopaminérgicos e o tratamento da disfunção erétil |
title_full |
Agentes dopaminérgicos e o tratamento da disfunção erétil |
title_fullStr |
Agentes dopaminérgicos e o tratamento da disfunção erétil |
title_full_unstemmed |
Agentes dopaminérgicos e o tratamento da disfunção erétil |
title_sort |
agentes dopaminérgicos e o tratamento da disfunção erétil |
publisher |
Sociedade Brasileira de Química |
series |
Química Nova |
issn |
0100-4042 1678-7064 |
publishDate |
2004-01-01 |
description |
The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopaminergic agents to elicit penile erection has been described since 1975 and successively confirmed by numerous studies. The development of apomorphine SL (dopaminergic non selective agonist) to enhance erectile function represents a new pharmacological approach to the management of erectile dysfunction using CNS drugs. The search for selective D4 dopaminergic agents is being explored by some research groups and pharmaceutical companies. |
topic |
erectile dysfunction dopaminergic agents apomorphine |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020 |
work_keys_str_mv |
AT nevesgilda agentesdopaminergicoseotratamentodadisfuncaoeretil AT ratesstelamk agentesdopaminergicoseotratamentodadisfuncaoeretil AT fragacarlosam agentesdopaminergicoseotratamentodadisfuncaoeretil AT barreiroeliezerj agentesdopaminergicoseotratamentodadisfuncaoeretil |
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