Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed
Mumps is a vaccine-preventable infectious disease diffuse worldwide. The implementation of mumps vaccination reduced largely the spread of infection. On 11,327 Medical School students the prevalence of mumps positive antibodies was evaluated according to dose/doses of vaccine, year of birth and sex....
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doaj-2d97a889fb6d494aaf40c169e9c107c22021-07-23T14:11:30ZengMDPI AGViruses1999-49152021-07-01131311131110.3390/v13071311Response to Vaccination against Mumps in Medical Students: Two Doses Are NeededAndrea Trevisan0Angelo Moretto1Chiara Bertoncello2Annamaria Nicolli3Stefano Maso4Maria Luisa Scapellato5Paola Mason6Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, via Giustiniani 2, 35128 Padova, ItalyMumps is a vaccine-preventable infectious disease diffuse worldwide. The implementation of mumps vaccination reduced largely the spread of infection. On 11,327 Medical School students the prevalence of mumps positive antibodies was evaluated according to dose/doses of vaccine, year of birth and sex. Compliance to mumps vaccine was low in students born before 1990 but increased consistently after this year, above all compliance to two doses, due to the implementation of the vaccine offer. Positivity of mumps antibodies is significantly (<i>p</i> < 0.0001) lower in students vaccinated once (71.2%) compared to those vaccinated twice (85.4%). In addition, students born after 1995, largely vaccinated twice, showed a seropositivity near to 90%. Further, females had a significantly (<i>p</i> < 0.0001) higher proportion of positive antibodies after vaccination than males, both one (74.6% vs. 64.7%) and two doses (86.8% vs. 82.9%). Finally, seropositivity after two vaccine doses remains high (86.1%) even 15 years after the second dose. In conclusion, the research highlighted that vaccination against mumps reaches a good level of coverage only after two doses of vaccine persisting at high levels over 15 years and induces a more significant response in females.https://www.mdpi.com/1999-4915/13/7/1311mumpsvaccinationhealth care workersmedical students |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrea Trevisan Angelo Moretto Chiara Bertoncello Annamaria Nicolli Stefano Maso Maria Luisa Scapellato Paola Mason |
spellingShingle |
Andrea Trevisan Angelo Moretto Chiara Bertoncello Annamaria Nicolli Stefano Maso Maria Luisa Scapellato Paola Mason Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed Viruses mumps vaccination health care workers medical students |
author_facet |
Andrea Trevisan Angelo Moretto Chiara Bertoncello Annamaria Nicolli Stefano Maso Maria Luisa Scapellato Paola Mason |
author_sort |
Andrea Trevisan |
title |
Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed |
title_short |
Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed |
title_full |
Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed |
title_fullStr |
Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed |
title_full_unstemmed |
Response to Vaccination against Mumps in Medical Students: Two Doses Are Needed |
title_sort |
response to vaccination against mumps in medical students: two doses are needed |
publisher |
MDPI AG |
series |
Viruses |
issn |
1999-4915 |
publishDate |
2021-07-01 |
description |
Mumps is a vaccine-preventable infectious disease diffuse worldwide. The implementation of mumps vaccination reduced largely the spread of infection. On 11,327 Medical School students the prevalence of mumps positive antibodies was evaluated according to dose/doses of vaccine, year of birth and sex. Compliance to mumps vaccine was low in students born before 1990 but increased consistently after this year, above all compliance to two doses, due to the implementation of the vaccine offer. Positivity of mumps antibodies is significantly (<i>p</i> < 0.0001) lower in students vaccinated once (71.2%) compared to those vaccinated twice (85.4%). In addition, students born after 1995, largely vaccinated twice, showed a seropositivity near to 90%. Further, females had a significantly (<i>p</i> < 0.0001) higher proportion of positive antibodies after vaccination than males, both one (74.6% vs. 64.7%) and two doses (86.8% vs. 82.9%). Finally, seropositivity after two vaccine doses remains high (86.1%) even 15 years after the second dose. In conclusion, the research highlighted that vaccination against mumps reaches a good level of coverage only after two doses of vaccine persisting at high levels over 15 years and induces a more significant response in females. |
topic |
mumps vaccination health care workers medical students |
url |
https://www.mdpi.com/1999-4915/13/7/1311 |
work_keys_str_mv |
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