An objective approach for Burkholderia pseudomallei strain selection as challenge material for medical countermeasures efficacy testing

An objective approach for Burkholderia pseudomallei strain selection as challenge material for medical countermeasures efficacy testing

Burkholderia pseudomallei is the causative agent of melioidosis, a rare disease of biodefense concern with high mortality and extreme difficulty in treatment. No human vaccines are available that protect against B. pseudomallei infection, and with the current limitations of antibiotic treatment, the...

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Bibliographic Details
Main Authors: Kristopher E. Van Zandt, Apichai eTuanyok, Paul eKeim, Richard L Warren, H. Carl eGelhaus
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Burkholderia
Genome
Virulence
Sequencing
Animal Models
aerosol
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00120/full

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