Utility of urine cytology in evaluating hematuria with sonographically suspected bladder lesion in patients older than 50 years

• Main Authors: Hussam Eldin Helmy Mady, Abd Alhady Mohammad Omar, Mohamed Abd-Alla Elgammal, Ghada Hosny Mohamed Ibrahim
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Urology Annals
• Subjects: Bladder cancer; hematuria; urine cytology
• Online Access: http://www.urologyannals.com/article.asp?issn=0974-7796;year=2014;volume=6;issue=3;spage=212;epage=217;aulast=Helmy
• ISSN: 0974-7796; 0974-7834

Purpose: Investigate the utility of urine cytology (UC) in patients older than 50 years with hematuria and sonographically suspected bladder lesion. Patients and Methods: Between April 2010 and June 2012, 152 patients above 50 years suffering from hematuria were included in this study. In all patients, ultrasound revealed a lesion suspected to be bladder cancer. Voided urine specimens were taken from all patients and transported to Pathology laboratory and processed within 1-3 h. All patients have undergone a cystoscopy examination and biopsy was taken from any suspicious lesion. The cytological diagnosis was reported as one of three categories, positive or negative or suspicious for malignancy. Results: One hundred thirty three (87.5%) patients in this study proved to have bladder carcinoma in histopathological examination. The sensitivity of UC was 53.4% and only five patients were suspicious. Percentage of positive cytology was highest among patients having gross hematuria (51.3%), posterior wall lesions (75%), papillonodular configuration (81.8%), invasive cancer (59.1%) and bilharzial affection (52.5%). Conclusion: Hematuria in patients older than 50 years with sonographically suspected bladder lesion mandates cystoscopy and biopsy. UC does not add more significant information in this group of patients.