Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid
Cichoric acid (CA) is a derivative of both caffeic acid and tartaric acid. It was isolated for the first time from <i>Cichorium intybus</i> L. (chicory) but it also occurs in significant amounts in <i>Echinacea</i>, particularly <i>E. purpurea</i>, dandelion leave...
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doaj-2e0a55f536c143b793fcbc01052385fd2020-11-25T02:41:22ZengMDPI AGMaterials1996-19442020-07-01133102310210.3390/ma13143102Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric AcidGrzegorz Świderski0Agata Jabłońska-Trypuć1Monika Kalinowska2Renata Świsłocka3Danuta Karpowicz4Marta Magnuszewska5Włodzimierz Lewandowski6Department of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, PolandDepartment of Food Analysis, Institute of Agricultural and Food Biotechnology, Rakowiecka 36 Street, 02-532 Warsaw, PolandCichoric acid (CA) is a derivative of both caffeic acid and tartaric acid. It was isolated for the first time from <i>Cichorium intybus</i> L. (chicory) but it also occurs in significant amounts in <i>Echinacea</i>, particularly <i>E. purpurea</i>, dandelion leaves, basil, lemon balm and in aquatic plants, including algae and sea grasses. It has a wide spectrum of biological properties, including antioxidant, antiviral, anti-inflammatory and other. The work yielded cichoric acid complexes with selected transition metals, i.e., copper(II), nickel(II), zinc(II) and cobalt(II). In this work the dependency between the molecular structure and biological activity was discussed. The molecular structure was studied by means of infrared spectroscopy (Fourier transform infrared (FT-IR) Raman (FT-Raman)), electronic absorption spectroscopy (ultraviolet–visible (UV/VIS)) and theoretical calculations (density functional theory (DFT), Hartree–Fock (HF)). Understanding the mechanism of the effect of metals on the electronic system of ligands with biological importance will facilitate in the future the search for new, effective and natural antioxidants. The composition of the studied complexes in aqueous solutions was determined at a constant pH by the Job’s method. Antioxidative properties of the tested compounds were determined using the ferric-reducing antioxidant power (FRAP), DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate free radical method), cupric-reducing antioxidant capacity (CUPRAC) and Superoxide Dismutase Activity Assay (SOD).https://www.mdpi.com/1996-1944/13/14/3102cichoric acidcaffeic acidantioxidant propertiesmetal complexes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Grzegorz Świderski Agata Jabłońska-Trypuć Monika Kalinowska Renata Świsłocka Danuta Karpowicz Marta Magnuszewska Włodzimierz Lewandowski |
spellingShingle |
Grzegorz Świderski Agata Jabłońska-Trypuć Monika Kalinowska Renata Świsłocka Danuta Karpowicz Marta Magnuszewska Włodzimierz Lewandowski Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid Materials cichoric acid caffeic acid antioxidant properties metal complexes |
author_facet |
Grzegorz Świderski Agata Jabłońska-Trypuć Monika Kalinowska Renata Świsłocka Danuta Karpowicz Marta Magnuszewska Włodzimierz Lewandowski |
author_sort |
Grzegorz Świderski |
title |
Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid |
title_short |
Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid |
title_full |
Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid |
title_fullStr |
Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid |
title_full_unstemmed |
Spectroscopic, Theoretical and Antioxidant Study of 3d-Transition Metals (Co (II), Ni(II), Cu(II), Zn(II) Complexes with Cichoric Acid |
title_sort |
spectroscopic, theoretical and antioxidant study of 3d-transition metals (co (ii), ni(ii), cu(ii), zn(ii) complexes with cichoric acid |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2020-07-01 |
description |
Cichoric acid (CA) is a derivative of both caffeic acid and tartaric acid. It was isolated for the first time from <i>Cichorium intybus</i> L. (chicory) but it also occurs in significant amounts in <i>Echinacea</i>, particularly <i>E. purpurea</i>, dandelion leaves, basil, lemon balm and in aquatic plants, including algae and sea grasses. It has a wide spectrum of biological properties, including antioxidant, antiviral, anti-inflammatory and other. The work yielded cichoric acid complexes with selected transition metals, i.e., copper(II), nickel(II), zinc(II) and cobalt(II). In this work the dependency between the molecular structure and biological activity was discussed. The molecular structure was studied by means of infrared spectroscopy (Fourier transform infrared (FT-IR) Raman (FT-Raman)), electronic absorption spectroscopy (ultraviolet–visible (UV/VIS)) and theoretical calculations (density functional theory (DFT), Hartree–Fock (HF)). Understanding the mechanism of the effect of metals on the electronic system of ligands with biological importance will facilitate in the future the search for new, effective and natural antioxidants. The composition of the studied complexes in aqueous solutions was determined at a constant pH by the Job’s method. Antioxidative properties of the tested compounds were determined using the ferric-reducing antioxidant power (FRAP), DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate free radical method), cupric-reducing antioxidant capacity (CUPRAC) and Superoxide Dismutase Activity Assay (SOD). |
topic |
cichoric acid caffeic acid antioxidant properties metal complexes |
url |
https://www.mdpi.com/1996-1944/13/14/3102 |
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