A novel role for Tm7sf2 gene in regulating TNFα expression.
We have explored the role of Tm7sf2 gene, which codifies for 3β-hydroxysterol Δ14-reductase, an endoplasmic reticulum resident protein, in the sensitivity to endoplasmic reticulum stress and in the resulting inflammatory response. We used mouse embryonic fibroblasts, derived from Tm7sf2(+/+) and Tm7...
Main Authors: | Ilaria Bellezza, Rita Roberti, Leonardo Gatticchi, Rachele Del Sordo, Maria Grazia Rambotti, Maria Cristina Marchetti, Angelo Sidoni, Alba Minelli |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3720723?pdf=render |
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