Voxel-wise deviations from healthy aging for the detection of region-specific atrophy

The identification of pathological atrophy in MRI scans requires specialized training, which is scarce outside dedicated centers. We sought to investigate the clinical usefulness of computer-generated representations of local grey matter (GM) loss or increased volume of cerebral fluids (CSF) as norm...

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Bibliographic Details
Main Authors: Stefan Klöppel, Shan Yang, Elias Kellner, Marco Reisert, Bernhard Heimbach, Horst Urbach, Jennifer Linn, Stefan Weidauer, Tamara Andres, Maximilian Bröse, Jacob Lahr, Niklas Lützen, Philipp T. Meyer, Jessica Peter, Ahmed Abdulkadir, Sabine Hellwig, Karl Egger
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218302882