Strategies in regulating glioblastoma signaling pathways and anti-invasion therapy.

Glioblastoma multiforme is one of the most invasive type of glial tumors, which rapidly grows and commonly spreads into nearby brain tissue. It is a devastating brain cancer that often results in death within approximately 12 to 15 months after diagnosis. In this work, optimal control theory was app...

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Bibliographic Details
Main Authors: Eunok Jung, Aurelio A de Los Reyes V, Kurt Jan A Pumares, Yangjin Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215547

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