Title: insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides

Title: insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides

Abstract Background Protein aggregation is a biological event observed in expression systems in which the recombinant protein is produced under stressful conditions surpassing the homeostasis of the protein quality control system. In addition, protein aggregation is also related to conformational di...

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Bibliographic Details
Main Authors: Jose Vicente Carratalá, Andrés Cisneros, Elijah Hellman, Antonio Villaverde, Neus Ferrer-Miralles
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Microbial Cell Factories
Subjects:
Recombinant protein
Inclusion body formation
Protein aggregation
Intermolecular interaction
Antimicrobial peptides
Online Access:https://doi.org/10.1186/s12934-021-01524-3

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