Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
Abstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-04-01
|
Series: | Clinical Case Reports |
Subjects: | |
Online Access: | https://doi.org/10.1002/ccr3.2714 |
id |
doaj-2e30d392dfbb4984928220a55546f064 |
---|---|
record_format |
Article |
spelling |
doaj-2e30d392dfbb4984928220a55546f0642020-11-25T03:25:47ZengWileyClinical Case Reports2050-09042020-04-018467567910.1002/ccr3.2714Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndromeDivya Namboodiri0Hui Yi Ng1Aakansha Zala2John Magnussen3Andrew Davidson4Bernard Champion5Veronica Preda6Department of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaAbstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS.https://doi.org/10.1002/ccr3.2714Klinefelter syndromemacrogonadotropinomaperiventricular white matter changespulmonary embolismvenous thromboembolism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Divya Namboodiri Hui Yi Ng Aakansha Zala John Magnussen Andrew Davidson Bernard Champion Veronica Preda |
spellingShingle |
Divya Namboodiri Hui Yi Ng Aakansha Zala John Magnussen Andrew Davidson Bernard Champion Veronica Preda Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome Clinical Case Reports Klinefelter syndrome macrogonadotropinoma periventricular white matter changes pulmonary embolism venous thromboembolism |
author_facet |
Divya Namboodiri Hui Yi Ng Aakansha Zala John Magnussen Andrew Davidson Bernard Champion Veronica Preda |
author_sort |
Divya Namboodiri |
title |
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome |
title_short |
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome |
title_full |
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome |
title_fullStr |
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome |
title_full_unstemmed |
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome |
title_sort |
macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with klinefelter syndrome |
publisher |
Wiley |
series |
Clinical Case Reports |
issn |
2050-0904 |
publishDate |
2020-04-01 |
description |
Abstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS. |
topic |
Klinefelter syndrome macrogonadotropinoma periventricular white matter changes pulmonary embolism venous thromboembolism |
url |
https://doi.org/10.1002/ccr3.2714 |
work_keys_str_mv |
AT divyanamboodiri macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT huiying macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT aakanshazala macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT johnmagnussen macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT andrewdavidson macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT bernardchampion macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome AT veronicapreda macrogonadotropinomaavenousthromboemboliceventandasymptomaticextensiveperiventricularwhitematterchangesinapatientwithklinefeltersyndrome |
_version_ |
1724595772788310016 |