Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome

Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome

Abstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with...

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Main Authors: Divya Namboodiri, Hui Yi Ng, Aakansha Zala, John Magnussen, Andrew Davidson, Bernard Champion, Veronica Preda
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Clinical Case Reports
Subjects:
Klinefelter syndrome
macrogonadotropinoma
periventricular white matter changes
pulmonary embolism
venous thromboembolism
Online Access:https://doi.org/10.1002/ccr3.2714
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spelling doaj-2e30d392dfbb4984928220a55546f0642020-11-25T03:25:47ZengWileyClinical Case Reports2050-09042020-04-018467567910.1002/ccr3.2714Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndromeDivya Namboodiri0Hui Yi Ng1Aakansha Zala2John Magnussen3Andrew Davidson4Bernard Champion5Veronica Preda6Department of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaDepartment of Clinical Medicine Macquarie University Sydney NSW AustraliaAbstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS.https://doi.org/10.1002/ccr3.2714Klinefelter syndromemacrogonadotropinomaperiventricular white matter changespulmonary embolismvenous thromboembolism
collection DOAJ
language English
format Article
sources DOAJ
author Divya Namboodiri
Hui Yi Ng
Aakansha Zala
John Magnussen
Andrew Davidson
Bernard Champion
Veronica Preda
spellingShingle Divya Namboodiri
Hui Yi Ng
Aakansha Zala
John Magnussen
Andrew Davidson
Bernard Champion
Veronica Preda
Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
Clinical Case Reports
Klinefelter syndrome
macrogonadotropinoma
periventricular white matter changes
pulmonary embolism
venous thromboembolism
author_facet Divya Namboodiri
Hui Yi Ng
Aakansha Zala
John Magnussen
Andrew Davidson
Bernard Champion
Veronica Preda
author_sort Divya Namboodiri
title Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
title_short Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
title_full Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
title_fullStr Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
title_full_unstemmed Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
title_sort macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with klinefelter syndrome
publisher Wiley
series Clinical Case Reports
issn 2050-0904
publishDate 2020-04-01
description Abstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS.
topic Klinefelter syndrome
macrogonadotropinoma
periventricular white matter changes
pulmonary embolism
venous thromboembolism
url https://doi.org/10.1002/ccr3.2714
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