A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus.

A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus.

Variation in the TGF-β signaling pathway is emerging as an important mechanism by which gonadal sex determination is controlled in teleosts. Here we show that amhy, a Y-specific duplicate of the anti-Müllerian hormone (amh) gene, induces male sex determination in Nile tilapia. amhy is a tandem dupli...

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Bibliographic Details
Main Authors: Minghui Li, Yunlv Sun, Jiue Zhao, Hongjuan Shi, Sheng Zeng, Kai Ye, Dongneng Jiang, Linyan Zhou, Lina Sun, Wenjing Tao, Yoshitaka Nagahama, Thomas D Kocher, Deshou Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4654491?pdf=render

Internet

http://europepmc.org/articles/PMC4654491?pdf=render

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