GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation

GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation

Summary: Precise control of gene expression during development is orchestrated by transcription factors and co-regulators including chromatin modifiers. How particular chromatin-modifying enzymes affect specific developmental processes is not well defined. Here, we report that GCN5, a histone acetyl...

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Bibliographic Details
Main Authors: Li Wang, Evangelia Koutelou, Calley Hirsch, Ryan McCarthy, Andria Schibler, Kevin Lin, Yue Lu, Collene Jeter, Jianjun Shen, Michelle C. Barton, Sharon Y.R. Dent
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Stem Cell Reports
Subjects:
GCN5
MYC
FGF signaling
embryoid body
chromatin
histone H3
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117305167

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http://www.sciencedirect.com/science/article/pii/S2213671117305167

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