Spontaneous Regression of a Carcinoid Tumor following Pregnancy

Spontaneous Regression of a Carcinoid Tumor following Pregnancy

We present a case of spontaneous regression of a neuroendocrine tumor following pregnancy in the absence of chemotherapy, radiotherapy, or alternative medicine (including herbal medicine). The diagnosis of a nonsecretory carcinoid tumor was confirmed using CT imaging, octreotide scan, and histology...

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Main Authors: A. Sewpaul, D. Bargiela, A. James, S. J. Johnson, J. J. French
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/481823
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spelling doaj-2e66f97528b348fc9ab46e75f0908a522020-11-24T21:45:39ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/481823481823Spontaneous Regression of a Carcinoid Tumor following PregnancyA. Sewpaul0D. Bargiela1A. James2S. J. Johnson3J. J. French4Department of HPB and Transplant Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKDepartment of HPB and Transplant Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKDepartment of Endocrinology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UKDepartment of Cellular Pathology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UKDepartment of HPB and Transplant Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKWe present a case of spontaneous regression of a neuroendocrine tumor following pregnancy in the absence of chemotherapy, radiotherapy, or alternative medicine (including herbal medicine). The diagnosis of a nonsecretory carcinoid tumor was confirmed using CT imaging, octreotide scan, and histology. Furthermore, serial imaging has demonstrated spontaneous regression of the carcinoid suggesting that pregnancy did not worsen the course of the disease but instead may have contributed to tumour regression. We discuss mechanisms underlying tumour regression and the possible effect of pregnancy on these processes.http://dx.doi.org/10.1155/2014/481823
collection DOAJ
language English
format Article
sources DOAJ
author A. Sewpaul
D. Bargiela
A. James
S. J. Johnson
J. J. French
spellingShingle A. Sewpaul
D. Bargiela
A. James
S. J. Johnson
J. J. French
Spontaneous Regression of a Carcinoid Tumor following Pregnancy
Case Reports in Endocrinology
author_facet A. Sewpaul
D. Bargiela
A. James
S. J. Johnson
J. J. French
author_sort A. Sewpaul
title Spontaneous Regression of a Carcinoid Tumor following Pregnancy
title_short Spontaneous Regression of a Carcinoid Tumor following Pregnancy
title_full Spontaneous Regression of a Carcinoid Tumor following Pregnancy
title_fullStr Spontaneous Regression of a Carcinoid Tumor following Pregnancy
title_full_unstemmed Spontaneous Regression of a Carcinoid Tumor following Pregnancy
title_sort spontaneous regression of a carcinoid tumor following pregnancy
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2014-01-01
description We present a case of spontaneous regression of a neuroendocrine tumor following pregnancy in the absence of chemotherapy, radiotherapy, or alternative medicine (including herbal medicine). The diagnosis of a nonsecretory carcinoid tumor was confirmed using CT imaging, octreotide scan, and histology. Furthermore, serial imaging has demonstrated spontaneous regression of the carcinoid suggesting that pregnancy did not worsen the course of the disease but instead may have contributed to tumour regression. We discuss mechanisms underlying tumour regression and the possible effect of pregnancy on these processes.
url http://dx.doi.org/10.1155/2014/481823
work_keys_str_mv AT asewpaul spontaneousregressionofacarcinoidtumorfollowingpregnancy
AT dbargiela spontaneousregressionofacarcinoidtumorfollowingpregnancy
AT ajames spontaneousregressionofacarcinoidtumorfollowingpregnancy
AT sjjohnson spontaneousregressionofacarcinoidtumorfollowingpregnancy
AT jjfrench spontaneousregressionofacarcinoidtumorfollowingpregnancy
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