A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.

A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.

Since activation of the PI3K/(protein kinase B; PKB/akt) pathway has been shown to alter muscle mass and growth, the aim of this study was to determine whether resistance exercise increased insulin like growth factor (IGF) I/phosphoinositide 3-kinase (PI3K) signalling and whether altering PI(3,4,5)P...

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Bibliographic Details
Main Authors: D Lee Hamilton, Andrew Philp, Matthew G MacKenzie, Keith Baar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2905373?pdf=render

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