Efficacy of imiquimod-based transcutaneous immunization using a nano-dispersed emulsion gel formulation.
BACKGROUND:Transcutaneous immunization (TCI) approaches utilize skin associated lymphatic tissues to elicit specific immune responses. In this context, the imidazoquinoline derivative imiquimod formulated in Aldara applied onto intact skin together with a cytotoxic T lymphocyte (CTL) epitope induces...
Main Authors: | Pamela Stein, Karsten Gogoll, Stefan Tenzer, Hansjörg Schild, Stefan Stevanovic, Peter Langguth, Markus P Radsak |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4099367?pdf=render |
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