Increased RNA editing in maternal immune activation model of neurodevelopmental disease

Interferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.

Bibliographic Details
Main Authors:	Hadas Tsivion-Visbord, Eli Kopel, Ariel Feiglin, Tamar Sofer, Ran Barzilay, Tali Ben-Zur, Orly Yaron, Daniel Offen, Erez Y. Levanon
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-19048-6

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spelling	doaj-2ed2b8422be94f928e72f7b89c81639b2021-05-11T08:18:39ZengNature Publishing GroupNature Communications2041-17232020-10-0111111310.1038/s41467-020-19048-6Increased RNA editing in maternal immune activation model of neurodevelopmental diseaseHadas Tsivion-Visbord0Eli Kopel1Ariel Feiglin2Tamar Sofer3Ran Barzilay4Tali Ben-Zur5Orly Yaron6Daniel Offen7Erez Y. Levanon8Sackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversityDepartment of Biomedical Informatics, Harvard Medical SchoolDepartments of Medicine and of Biostatistics, Harvard UniversityLifespan Brain Institute Children’s Hospital of Philadelphia and Penn Medicine; the Department of Child and Adolescent Psychiatry and Behavioral Sciences, CHOPSackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversitySackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversityInterferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.https://doi.org/10.1038/s41467-020-19048-6
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon
spellingShingle	Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon Increased RNA editing in maternal immune activation model of neurodevelopmental disease Nature Communications
author_facet	Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon
author_sort	Hadas Tsivion-Visbord
title	Increased RNA editing in maternal immune activation model of neurodevelopmental disease
title_short	Increased RNA editing in maternal immune activation model of neurodevelopmental disease
title_full	Increased RNA editing in maternal immune activation model of neurodevelopmental disease
title_fullStr	Increased RNA editing in maternal immune activation model of neurodevelopmental disease
title_full_unstemmed	Increased RNA editing in maternal immune activation model of neurodevelopmental disease
title_sort	increased rna editing in maternal immune activation model of neurodevelopmental disease
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-10-01
description	Interferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.
url	https://doi.org/10.1038/s41467-020-19048-6
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Increased RNA editing in maternal immune activation model of neurodevelopmental disease

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