Current status and future perspectives of HLA-edited induced pluripotent stem cells

Current status and future perspectives of HLA-edited induced pluripotent stem cells

Abstract In 2007, Human-induced pluripotent stem cells (iPSCs) were generated by transducing four genes (Oct3/4, Sox2, Klf4, c-Myc). Because iPSCs can differentiate into any types of cells in the body and have fewer ethical issues compared to embryonic stem (ES) cells, application of iPSCs for regen...

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Bibliographic Details
Main Authors: Keiko Koga, Bo Wang, Shin Kaneko
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Inflammation and Regeneration
Online Access:http://link.springer.com/article/10.1186/s41232-020-00132-9

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