CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS

• Main Author: A. M. MАLIK
• Format: Article
• Language: Russian
• Published: NEW TERRA Publishing House 2017-10-01
• Series: Tuberkulez i Bolezni Lëgkih
• Subjects: xpert mtb/rif; drug susceptible tuberculosis; drug resistant tuberculosis
• Online Access: https://www.tibl-journal.com/jour/article/view/1042

The goal of the study: to evaluate treatment efficiency of pulmonary tuberculosis patients resistant to rifampicin when treatment was prescribed based on the results of Xpert MBT/RIF. The social and clinical structure was retrospectively analyzed in 165 new pulmonary tuberculosis patients, treated in the in-patient unit of Municipal Clinical Phthisiopulmonary Hospital (Kishineu Mun.). Patients were divided into 2 groups: the main group included 85 patients, in whom the result of Xpert MTB/RIF was positive and resistant to rifampicin, the control group included 80 patients in whom the result of Xpert MTB/RIF was positive and susceptible to rifampicin; certain parameters of the groups were compared. Only 65/80 (81.2%) patients of the control group had a complete treatment course, and 61/85 (71.8%) of the main group, the rest of the patients was lost to follow-up. Evaluation of the outcomes of the complete treatment course showed no confident difference between drug susceptible tuberculosis patients and those resistant to rifampicin, provided that treatment was prescribed with the consideration of Xpert MBT/RIF data.