Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial–Mesenchymal Transition In Gastric Cancer

Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial–Mesenchymal Transition In Gastric Cancer

Di Feng,1 Xiaoyu Yu,1 Xing Tian,2 Hongxue Meng,1 Yang Jiang,1 HongTao Song,1 WenQi Li,1 HaoCheng Zhang,3 Jingshu Geng1 1Department of Pathology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150081, People’s Republic of China; 2Department of Microbiology and Center of Inf...

Full description

Bibliographic Details
Main Authors:	Feng D, Yu X, Tian X, Meng H, Jiang Y, Song H, Li W, Zhang H, Geng J
Format:	Article
Language:	English
Published:	Dove Medical Press 2019-10-01
Series:	Cancer Management and Research
Subjects:	metadherin gastric cancer CD44 β-catenin cancer stem cells
Online Access:	https://www.dovepress.com/metadherin-promotes-malignant-phenotypes-and-induces-beta-catenin-nucl-peer-reviewed-article-CMAR

Similar Items

Metadherin regulates epithelial–mesenchymal transition in carcinoma
by: Wang Z, et al.
Published: (2016-04-01)

Metadherin: A Therapeutic Target in Multiple Cancers
by: Gourav Dhiman, et al.
Published: (2019-05-01)

12-Lipoxygenase promotes epithelial–mesenchymal transition via the Wnt/β-catenin signaling pathway in gastric cancer cells
by: Yang XH, et al.
Published: (2019-07-01)

MicroRNA-559 Plays an Inhibitory Role in the Malignant Progression of Glioblastoma Cells by Directly Targeting Metadherin [Retraction]
by: Yang F, et al.
Published: (2021-09-01)

Upregulated RACK1 attenuates gastric cancer cell growth and epithelial–mesenchymal transition via suppressing Wnt/β-catenin signaling
by: Zhu L, et al.
Published: (2019-06-01)

MicroRNA-559 plays an inhibitory role in the malignant progression of glioblastoma cells by directly targeting metadherin
by: Yang F, et al.
Published: (2019-06-01)

Circular RNA Circ-03955 Promotes Epithelial-Mesenchymal Transition in Osteosarcoma by Regulating miR-3662/Metadherin Pathway
by: Zhengguang Wang, et al.
Published: (2020-11-01)

Simvastatin Inhibits the Malignant Behaviors of Gastric Cancer Cells by Simultaneously Suppressing YAP and β-Catenin Signaling
by: Liu Q, et al.
Published: (2020-03-01)

MicroRNA-618 Directly Targets Metadherin mRNA To Suppress The Malignant Phenotype Of Osteosarcoma Cells By Reducing PTEN-AKT Pathway Output
by: Li B, et al.
Published: (2019-11-01)

Metadherin-mediated Cell Proliferation and Paclitaxel Resistance in Nasopharyngeal Carcinoma
by: YU Changyun, et al.
Published: (2019-01-01)

MicroRNA-618 Directly Targets Metadherin mRNA to Suppress the Malignant Phenotype of Osteosarcoma Cells by Reducing PTEN-AKT Pathway Output [Retraction]
by: Li B, et al.
Published: (2021-10-01)

Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through β-catenin/Erk/Akt signaling in gastric cancer
by: Biao Geng, et al.
Published: (2018-08-01)

MicroRNA-876 is sponged by long noncoding RNA LINC00707 and directly targets metadherin to inhibit breast cancer malignancy
by: Li T, et al.
Published: (2019-06-01)

Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin
by: Yen Thi-Kim Nguyen, et al.
Published: (2020-01-01)

IGHG1 upregulation promoted gastric cancer malignancy via AKT/GSK-3β/β-Catenin pathway
by: Xinyu Li, et al.
Published: (2021-07-01)

The Expression of Circulating miR-497 and Metadherin in Hepatocellular Carcinoma: Relation to the Tumor Characteristics and Patients’ Survival
by: Dina A. Ali, et al.
Published: (2021-08-01)

Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling
by: Ping MH
Published: (2020-11-01)

microRNA-877 Inhibits Malignant Progression of Colorectal Cancer by Directly Targeting MTDH and Regulating the PTEN/Akt Pathway [Retraction]
by: Zhang L, et al.
Published: (2021-09-01)

TRIM29 facilitates the epithelial-to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway
by: Juntao Sun, et al.
Published: (2019-02-01)

microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway
by: Zhang L, et al.
Published: (2019-04-01)

Lobaplatin inhibits breast cancer progression, cell proliferation while it induces cell apoptosis by downregulating MTDH expression
by: Tian W, et al.
Published: (2018-10-01)

Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of β-catenin by promoting δ-catenin ubiquitin degradation and upregulating SIK1
by: Cai, H., et al.
Published: (2022)

Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer
by: Zhiyang Peng, et al.
Published: (2020-06-01)

Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial–mesenchymal transition through Wnt/β-catenin pathway
by: Han-Hui Yao, et al.
Published: (2019-02-01)

Clinicopathological significance of E-cadherin, !-catenin and p53 expression in gastric adenocarinoma
by: Mohammad Reza Zali, et al.
Published: (2009-08-01)

RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway
by: Jian Su, et al.
Published: (2019-12-01)

Salinomycin repressed the epithelial–mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway
by: Li R, et al.
Published: (2017-02-01)

Mycoplasma hyorhinis infection promotes gastric cancer cell motility via β‐catenin signaling
by: Xia Liu, et al.
Published: (2019-09-01)

A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial–mesenchymal transition via the canonical Wnt/β-catenin signaling pathway
by: Xuxi Chen, et al.
Published: (2021-05-01)

Effect of Yes-associated Protein Knockdown on Apoptosis of Gastric Cancer BGC823 Cells Through Wnt/β-catenin Signaling Pathway
by: ZHANG Wei, et al.
Published: (2018-11-01)

Helicobacter pylori upregulates TRPC6 via Wnt/β-catenin signaling to promote gastric cancer migration and invasion
by: Song Y, et al.
Published: (2019-07-01)

A Therapeutic Strategy for Chemotherapy-Resistant Gastric Cancer via Destabilization of Both β-Catenin and RAS
by: Won-Ji Ryu, et al.
Published: (2019-04-01)

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway
by: Siwen Zhang, et al.
Published: (2021-01-01)

Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer
by: Wang F, et al.
Published: (2019-07-01)

Silencing of Long Non-Coding RNA HOTAIR Alleviates Epithelial–Mesenchymal Transition in Pancreatic Cancer via the Wnt/β-Catenin Signaling Pathway
by: Tang Y, et al.
Published: (2021-04-01)

Upregulation of Family with Sequence Similarity 83 Member D Expression Enhances Cell Proliferation and Motility via Activation of Wnt/β-Catenin Signaling and Predicts Poor Prognosis in Gastric Cancer [Corrigendum]
by: Wang F, et al.
Published: (2021-04-01)

Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer
by: Liang J, et al.
Published: (2019-04-01)

Inhibition of CCAR1, a Coactivator of β-Catenin, Suppresses the Proliferation and Migration of Gastric Cancer Cells
by: Te-Sheng Chang, et al.
Published: (2017-02-01)

Knockdown of IQGAP1 inhibits proliferation and epithelial–mesenchymal transition by Wnt/β-catenin pathway in thyroid cancer
by: Su D, et al.
Published: (2017-03-01)

Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancer
by: Shi M, et al.
Published: (2018-12-01)