Risk for Clostridiodes difficile Infection among Older Adults with Cancer
To assess whether risk for Clostridiodes difficile infection (CDI) is higher among older adults with cancer, we conducted a retrospective cohort study with a nested case–control analysis using population-based Surveillance, Epidemiology, and End Results–Medicare linked data for 2011. Among 93,566 Me...
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2019-09-01
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doaj-2f16cefc51274df3843959052dded4f12020-11-25T00:03:40ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-09-012591683168910.3201/eid2509.181142Risk for Clostridiodes difficile Infection among Older Adults with CancerMini KambojRenee L. GennarelliJennifer BriteKent SepkowitzAllison Lipitz-SnydermanTo assess whether risk for Clostridiodes difficile infection (CDI) is higher among older adults with cancer, we conducted a retrospective cohort study with a nested case–control analysis using population-based Surveillance, Epidemiology, and End Results–Medicare linked data for 2011. Among 93,566 Medicare beneficiaries, incident CDI and odds for acquiring CDI were higher among patients with than without cancer. Specifically, risk was significantly higher for those who had liquid tumors and higher for those who had recently diagnosed solid tumors and distant metastasis. These findings were independent of prior healthcare-associated exposure. This population-based assessment can be used to identify targets for prevention of CDI.https://wwwnc.cdc.gov/eid/article/25/9/18-1142_articleClostridium difficileClostridiodes difficilecanceragepopulationepidemiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mini Kamboj Renee L. Gennarelli Jennifer Brite Kent Sepkowitz Allison Lipitz-Snyderman |
spellingShingle |
Mini Kamboj Renee L. Gennarelli Jennifer Brite Kent Sepkowitz Allison Lipitz-Snyderman Risk for Clostridiodes difficile Infection among Older Adults with Cancer Emerging Infectious Diseases Clostridium difficile Clostridiodes difficile cancer age population epidemiology |
author_facet |
Mini Kamboj Renee L. Gennarelli Jennifer Brite Kent Sepkowitz Allison Lipitz-Snyderman |
author_sort |
Mini Kamboj |
title |
Risk for Clostridiodes difficile Infection among Older Adults with Cancer |
title_short |
Risk for Clostridiodes difficile Infection among Older Adults with Cancer |
title_full |
Risk for Clostridiodes difficile Infection among Older Adults with Cancer |
title_fullStr |
Risk for Clostridiodes difficile Infection among Older Adults with Cancer |
title_full_unstemmed |
Risk for Clostridiodes difficile Infection among Older Adults with Cancer |
title_sort |
risk for clostridiodes difficile infection among older adults with cancer |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2019-09-01 |
description |
To assess whether risk for Clostridiodes difficile infection (CDI) is higher among older adults with cancer, we conducted a retrospective cohort study with a nested case–control analysis using population-based Surveillance, Epidemiology, and End Results–Medicare linked data for 2011. Among 93,566 Medicare beneficiaries, incident CDI and odds for acquiring CDI were higher among patients with than without cancer. Specifically, risk was significantly higher for those who had liquid tumors and higher for those who had recently diagnosed solid tumors and distant metastasis. These findings were independent of prior healthcare-associated exposure. This population-based assessment can be used to identify targets for prevention of CDI. |
topic |
Clostridium difficile Clostridiodes difficile cancer age population epidemiology |
url |
https://wwwnc.cdc.gov/eid/article/25/9/18-1142_article |
work_keys_str_mv |
AT minikamboj riskforclostridiodesdifficileinfectionamongolderadultswithcancer AT reneelgennarelli riskforclostridiodesdifficileinfectionamongolderadultswithcancer AT jenniferbrite riskforclostridiodesdifficileinfectionamongolderadultswithcancer AT kentsepkowitz riskforclostridiodesdifficileinfectionamongolderadultswithcancer AT allisonlipitzsnyderman riskforclostridiodesdifficileinfectionamongolderadultswithcancer |
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1725432512536117248 |