Methadone induced hypoglycemia, improved on dose adjustment

There exists reports in the literature that connects opioids with hypoglycemia, primarily methadone. We present a case of new onset hypoglycemia in a patient with end stage renal disease who was chronically on methadone. After other causes have been ruled out including insulinoma, methadone induced...

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Bibliographic Details
Main Authors: Y. Otalora, S. Inkollu, S. Ursu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Clinical and Translational Endocrinology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214624520300162
Description
Summary:There exists reports in the literature that connects opioids with hypoglycemia, primarily methadone. We present a case of new onset hypoglycemia in a patient with end stage renal disease who was chronically on methadone. After other causes have been ruled out including insulinoma, methadone induced hypoglycemia was diagnosed. Making adjustments in doses of methadone showed improvement in hypoglycemia episodes. A brief review of literature about Methadone induced hypoglycemia which can probably be a drug class effect will be discussed here. Dose adjustments should be considered in such cases, especially in patients with comorbidities like renal disease.
ISSN:2214-6245