Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways
No other modality is more frequently represented in the prefrontal cortex than the auditory, but the role of auditory information in prefrontal functions is not well understood. Pathways from auditory association cortices reach distinct sites in the lateral, orbital, and medial surfaces of the prefr...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-04-01
|
Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00077/full |
id |
doaj-2f2533aad6ce4698a5f1ad2ec97cd528 |
---|---|
record_format |
Article |
spelling |
doaj-2f2533aad6ce4698a5f1ad2ec97cd5282020-11-24T23:13:43ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2014-04-01810.3389/fnins.2014.0007783572Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathwaysMaria eMedalla0Maria eMedalla1Helen eBarbas2Helen eBarbas3Helen eBarbas4Boston UniversityBoston UniversityBoston UniversityBoston UniversityBoston UniversityNo other modality is more frequently represented in the prefrontal cortex than the auditory, but the role of auditory information in prefrontal functions is not well understood. Pathways from auditory association cortices reach distinct sites in the lateral, orbital, and medial surfaces of the prefrontal cortex in rhesus monkeys. Among prefrontal areas, frontopolar area 10 has the densest interconnections with auditory association areas, spanning a large antero-posterior extent of the superior temporal gyrus from the temporal pole to auditory parabelt and belt regions. Moreover, auditory pathways make up the largest component of the extrinsic connections of area 10, suggesting a special relationship with the auditory modality. Here we review anatomic evidence showing that frontopolar area 10 is indeed the main frontal auditory field as the major recipient of auditory input in the frontal lobe and chief source of output to auditory cortices. Area 10 is thought to be the functional node for the most complex cognitive tasks of multitasking and keeping track of information for future decisions. These patterns suggest that the auditory association links of area 10 are critical for complex cognition. The first part of this review focuses on the organization of prefrontal-auditory pathways at the level of the system and the synapse, with a particular emphasis on area 10. Then we explore ideas on how the elusive role of area 10 in complex cognition may be related to the specialized relationship with auditory association cortices.http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00077/fullanterior cingulate cortexinhibitory neuronsfrontopolar cortexfrontal polearea 10synaptic pathways |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Maria eMedalla Maria eMedalla Helen eBarbas Helen eBarbas Helen eBarbas |
spellingShingle |
Maria eMedalla Maria eMedalla Helen eBarbas Helen eBarbas Helen eBarbas Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways Frontiers in Neuroscience anterior cingulate cortex inhibitory neurons frontopolar cortex frontal pole area 10 synaptic pathways |
author_facet |
Maria eMedalla Maria eMedalla Helen eBarbas Helen eBarbas Helen eBarbas |
author_sort |
Maria eMedalla |
title |
Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
title_short |
Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
title_full |
Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
title_fullStr |
Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
title_full_unstemmed |
Specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
title_sort |
specialized prefrontal auditory fields: organization of primate prefrontal-temporal pathways |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neuroscience |
issn |
1662-453X |
publishDate |
2014-04-01 |
description |
No other modality is more frequently represented in the prefrontal cortex than the auditory, but the role of auditory information in prefrontal functions is not well understood. Pathways from auditory association cortices reach distinct sites in the lateral, orbital, and medial surfaces of the prefrontal cortex in rhesus monkeys. Among prefrontal areas, frontopolar area 10 has the densest interconnections with auditory association areas, spanning a large antero-posterior extent of the superior temporal gyrus from the temporal pole to auditory parabelt and belt regions. Moreover, auditory pathways make up the largest component of the extrinsic connections of area 10, suggesting a special relationship with the auditory modality. Here we review anatomic evidence showing that frontopolar area 10 is indeed the main frontal auditory field as the major recipient of auditory input in the frontal lobe and chief source of output to auditory cortices. Area 10 is thought to be the functional node for the most complex cognitive tasks of multitasking and keeping track of information for future decisions. These patterns suggest that the auditory association links of area 10 are critical for complex cognition. The first part of this review focuses on the organization of prefrontal-auditory pathways at the level of the system and the synapse, with a particular emphasis on area 10. Then we explore ideas on how the elusive role of area 10 in complex cognition may be related to the specialized relationship with auditory association cortices. |
topic |
anterior cingulate cortex inhibitory neurons frontopolar cortex frontal pole area 10 synaptic pathways |
url |
http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00077/full |
work_keys_str_mv |
AT mariaemedalla specializedprefrontalauditoryfieldsorganizationofprimateprefrontaltemporalpathways AT mariaemedalla specializedprefrontalauditoryfieldsorganizationofprimateprefrontaltemporalpathways AT helenebarbas specializedprefrontalauditoryfieldsorganizationofprimateprefrontaltemporalpathways AT helenebarbas specializedprefrontalauditoryfieldsorganizationofprimateprefrontaltemporalpathways AT helenebarbas specializedprefrontalauditoryfieldsorganizationofprimateprefrontaltemporalpathways |
_version_ |
1725596867268444160 |