Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist
The diversity and uniqueness of flatworm G protein coupled receptors (GPCRs) provides impetus for identifying ligands useful as tools for studying flatworm biology, or as therapeutics for treating diseases caused by parasitic flatworm infections. To catalyse this discovery process, technologies opti...
Main Authors: | John D. Chan, Thomas Grab, Jonathan S. Marchant |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | International Journal for Parasitology: Drugs and Drug Resistance |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211320716300367 |
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